摘要
目的 分析不同年龄段颅脑损伤(TBI)患者睡眠障碍和认知功能障碍。方法 163例轻、中度TBI患者按年龄分为青年组(A1组,20~39岁,37例)、中年组(A2组,40~59岁,71例)和老年组(A3组,60~80岁,55例);选取无TBI病史的正常人群90例作为对照组,同样按年龄分为青年(B1)组、中年(B2)组和老年(B3)组,每组30例。采用匹兹堡睡眠质量指数和蒙特利尔认知评估基础量表分别评估患者的睡眠质量和认知功能情况。结果 163例TBI患者伤后6个月睡眠障碍发生率为42.3%,认知功能障碍发生率为34.4%,睡眠障碍和认知功能障碍共存的发生率为26.4%。对照组睡眠障碍发生率为23.3%,认知功能障碍发生率为8.9%,睡眠障碍和认知功能障碍共存的发生率为6.7%。A1组睡眠障碍、认知功能障碍、睡眠障碍和认知功能障碍共存的发生率均高于B1组(P<0.05);A2组认知功能障碍发生率高于B2组(P<0.05);A3组认知功能障碍、睡眠障碍和认知功能障碍共存的发生率高于B3组(P<0.05)。A3组睡眠障碍、认知功能障碍、睡眠障碍和认知功能障碍共存的发生率均高于A1组和A2组(P<0.05);B3组睡眠障碍、认知功能障碍发生率高于B1组和B2组(P<0.05)。结论 TBI患者睡眠障碍及认知功能障碍发生率较高,老年患者更易出现睡眠质量下降和认知功能障碍,甚至两种后遗症共同存在。
Objective To analyze the sleep disorder and cognitive dysfunction in the patients with traumatic brain injury(TBI) at different ages.Methods A total of 163 patients with mild and moderate TBI were divided into three groups of A1(20-39 years old, 37 cases),A2(40-59 years old, 71 cases) and A3(60-80 years old, 55 cases).A total of 90 healthy people without TBI were selected as the controls, who were also divided into three age groups of B1,B2 and B3 as in TBI patients with 30 cases each.Pittsburgh sleep quality index and the Montreal cognitive assessment basic scale were used to evaluate the sleep quality and cognitive function, respectively.Results The incidences of sleep disorder, cognitive dysfunction and co-occurrence of sleep and cognitive dysfunction were 42.3%,34.4% and 26.4% in the patients with mild and moderate TBI 6 months after injury, which were 23.3%,8.9% and 6.7% for the controls, respectively.The incidences of sleep disorder, cognitive dysfunction and co-occurrence of sleep and cognitive dysfunction in group A1 were higher than those in group B1(P<0.05).The incidence of cognitive dysfunction in group A2 was higher than that in group B2(P<0.05).The incidences of cognitive dysfunction and co-occurrence of sleep and cognitive dysfunction in group A3 were higher than those in group B3(P<0.05).The incidences of sleep disorder, cognitive dysfunction and co-occurrence of sleep and cognitive dysfunction in group A3 were higher than those in groups of A1 and A2(P<0.05).The incidences of sleep disorder and cognitive dysfunction in group B3 were higher than those in groups of B1 and B2(P<0.05).Conclusion The TBI patients have higher incidences of sleep and cognitive dysfunction.Elderly patients are more likely to have sleep quality decline and cognitive dysfunction, and even the two sequelae coexist.
作者
陈卫良
姚春瑜
朱祖建
苏稳
陈瑞
王冠军
CHEN Weiliang;YAO Chunyu;ZHU Zujian(Department of Neurosurgery,Haining People's Hospital,Haining 314400,CHINA)
出处
《江苏医药》
CAS
2022年第9期922-925,共4页
Jiangsu Medical Journal
基金
海宁市科技计划(2021058)。
关键词
颅脑损伤
睡眠
认知功能
年龄
Traumatic brain injury
Sleep
Cognition function
Age
