摘要
轻度认知障碍是处于正常脑老化与痴呆之间的一种不稳定的认知损害的临床状态,大部分患者将转化为痴呆。故轻度认知障碍是痴呆的高危人群,研究轻度认知损害对痴呆的预防和治疗具有非常重大意义。文中对轻度认知障碍的临床流行病学、量表筛查、影像及实验室诊断、药物治疗的新进展和新特点作一综述。
With the arrival of an aging population, the prevalence of dementia increases every year. The breakthrough of the treatment for dementia in recent years is rare, so early prevention of dementia has become the focus of the current study. Mild cognitive impairment, which is an unstable clinical stage between normal aging and dementia, is deemed to convert mostly to dementia. There- fore, mild cognitive impairment is at high risk of dementia. The study on mild cognitive impairment is very important to dementia pre- vention and treatment. Here the clinical epidemiology of mild cognitive impairment, scale screening, imaging and laboratory diagnosis, new drug treatment progress and new features are reviewed.
出处
《医学研究生学报》
CAS
北大核心
2012年第9期977-980,共4页
Journal of Medical Postgraduates
基金
国家自然科学基金(30970823)
关键词
轻度认知障碍
痴呆
磁共振成像
扩散张量成像
Mild cognitive impairment
Dementia
Magnetic resonance imaging
Diffusion tensor imaging
