摘要
目的:探讨糖尿病周围神经病变患者采用银杏达莫联合α-硫辛酸治疗的临床疗效。方法:选取医院2014年10月—2015年10月收治的62例糖尿病周围神经病变患者,按数字表法分为对照组和观察组,每组31例患者。对照组患者仅用α-硫辛酸治疗,观察组患者则采用银杏达莫联合α-硫辛酸治疗。对比两组患者的治疗效果、治疗前后的疼痛程度及神经传导速度。结果:观察组腓总神经、正中神经的运动神经传导速度和感觉神经传导速度明显优于对照组,具有统计学意义(t=9.18、6.51、3.50、7.56,P均<0.05);观察组治疗后的VSA评分(1.76±0.65)分与对照组的(2.48±0.73)分相比明显较低,差异具有统计学意义(P<0.05);观察组患者治疗的临床总有效率(90.32%)和对照组的(67.74%)相比明显提高,差异具有统计学意义(P<0.05)。结论:糖尿病周围神经病变患者采用银杏达莫联合α-硫辛酸治疗的效果显著,不仅可有效缓解患者四肢麻木、疼痛等症状,促进血液循环、营养神经,从而改善患者的运动、感觉神经传导速度,加快患者康复。
Objective： To investigate the clinical curative effect of ginkgo leaf extract and dipyridamole combined withα- lipoic acid in the treatment of patients with diabetic peripheral neuropathy. Methods： Sixty- two patients with diabetic peripheral neuropathy were divided into the control group and the observation group according to the digital table method,31 cases in each group. The patients of the control group were only given α- lipoic acid treatment and those of the observation group treated with ginkgo leaf extract and dipyridamole combined with α- lipoic acid. The treatment effect,the degree of pain before and after treatment and nerve conduction velocity of two groups were compared. Results： The peroneal nerve motor conduction velocity,median nerve conduction velocity and sensory nerve conduction velocity were statistically better than the control group＇s（ t = 9. 18,6. 51,3. 50,7. 56,P〈0. 05） and the difference was statistically significant（ P〈0. 05）. After treatment,VSA score of the observation group（ 1. 76 ± 0. 65） was significantly lower than the control group＇s（ 2. 48 ± 0. 73） and the difference was statistically significant（ P〈0. 05）. The clinical total effective rate（ 90. 32%） of the observation group were significantly improved than the control group＇s（ 67. 74%）（ P〈0. 05）.Conclusion： The ginkgo leaf extract and dipyridamole combined with α- lipoic acid in the treatment of patients with diabetic peripheral neuropathy has significant effect,which not only can effectively relieve patients with limb numbness,pain and other symptoms,but also can promote blood circulation and nerve nutrition,thereby improving patients＇ movement,feeling nerve conduction velocity and accelerate rehabilitation.
出处
《中华中医药学刊》
CAS
北大核心
2016年第5期1200-1202,共3页
Chinese Archives of Traditional Chinese Medicine
基金
嘉兴市科技局项目(20130708)
