摘要
目的探讨不同吸氧方式对提高高原部队军事作业能力的影响。方法将进驻海拔5 200 m守防1年的45名健康官兵,随机分成三组:对照组(n=15)未采取任何干预措施;吸氧1组(n=15)每天早晚各吸氧30 min;吸氧2组(n=15)每天早晚各吸氧60 min。两吸氧组采用低流量(2 L/min)持续鼻塞供氧。吸氧前和吸氧15 d后,分别进行二级定量负荷踏阶运动试验,评价PWC170和最大摄氧量(VO2max),踏阶运动结束后5 min采肘部静脉血检测血乳酸(BLA),超氧化物歧化酶(SOD)、丙二醛(MDA)、一氧化氮(NO)及其合酶(NOS)的活性及Hb浓度。结果吸氧后与吸氧前比较,吸氧1组VO2max、BLA、NO、NOS及Hb有统计学差异(P<0.05,P<0.01),PWC170、SOD、MDA无统计学差异(P>0.05);吸氧2组各项指标均有显著统计学差异(P<0.01);对照组各项指标差异无统计学意义。吸氧前,吸氧1组,吸氧2组与对照组各项指标比较均无统计学差异(P>0.05);吸氧1组与吸氧2组各项指标比较也无统计学差异(P>0.05)。吸氧后,吸氧1组与对照组VO2max和BLA比较有统计学差异(P<0.05),PWC170、NO、NOS、SOD、MDA及Hb无统计学差异;吸氧2组与对照组PWC170、VO2max、BLA、NOS及MDA比较有显著统计学差异(P<0.01),NO、SOD及Hb无统计学差异;吸氧1组与吸氧2组比较PWC170、NOS及MDA有统计学差异(P<0.05),其他几项指标无统计学差异。结论海拔5 200 m地区低流量吸氧可显著提高高原部队体能,两种吸氧方案均有效果,每天低流量持续吸氧60 min效果更为显著。
Objective To explore the effect of different oxygenation on military operations of plateau forces. Methods A total of45 healthy servicemen garrisoned at an altitude of 5 200 m for one year were divided into three groups at random,i. e. oxygen groupⅠ（ n = 15,oxygen inhalation for 30 minutes every morning and evening）,oxygen group Ⅱ（ n = 15,oxygen inhalation for 60 minutes every morning and evening） and control group（ n = 15,no oxygen inhalation）. The oxygen groups were treated with oxygen inhalation（ 2 L / min） via nasal congestion,and their PWC170 and VO2max were evaluated by two levels of rationing motor load test before and 15 days later after treatment. The blood lactic acid（ BLA）,nitric oxide（ NO）,nitric oxide synthetase（ NOS）,superoxide dismutase（ SOD）,malondialdehyde（ MDA） and hemoglobin（ Hb） were detected after rationing motor load test. Results Compared with before oxygenation,VO2 max,BLA,NO,NOS and Hb were of significant difference in the oxygen groupⅠ（ P〈0. 05,P〈0. 01）. In the oxygen group Ⅱ,all the indicators were of significant difference（ P〈0. 01）. The indicators of the control group were not statistically changed. Compared with that of the control group,the indicators of the oxygen groups were not statistically different before oxygenation（ P〈0. 05）. After oxygenation,the oxygen group Ⅰ＇s VO2 max and BLA were significant different from the control group＇s（ P〈0. 05） and the oxygen group Ⅱ＇s PWC170,VO2 max,BLA,NOS and MDA were significant different（ P〈0. 01）.Compared with that of the oxygen group Ⅰ,the indicators of the oxygen group Ⅱ were not statistically different before oxygenation（ P〉0. 05）,and after oxygenation PWC170,NOS and MDA were significant different（ P〈0. 05）. Conclusion The low flow oxygen inhalation may significantly improve the physical stamina of the servicemen stationed at an altitude of 5 200 m. The effect of oxygen therapy for one hour everyday is more significant.
出处
《临床军医杂志》
CAS
2015年第2期139-141,170,共4页
Clinical Journal of Medical Officers
关键词
高海拔
吸氧
PWC170
最大摄氧量
乳酸
自由基
血红蛋白
altitude
oxygen inhalation
PWC170
maximal oxygen uptake
lactic acid
free radical
hemoglobin
