摘要
目的观察功能运动训练在慢性肾脏病(CKD)患者治疗中的应用效果。方法选取2019年6月至2020年6月在秦皇岛市中医医院诊治的60例CKD患者为研究对象,按随机数表法分为对照组(n=30)和运动组(n=30)。对照组患者给予常规血液透析治疗,运动组患者在对照组基础上增加功能运动训练干预。于治疗前及治疗3个月后,比较两组患者透析充分性、血氧饱和度(SaO_(2))、营养状况、认知功能、焦虑抑郁程度,并测试6分钟步行距离(6MWT)、30 s坐立试验(30 s-STS),评价其生活质量。结果治疗后,运动组单室尿素清除率(spKt/V)、SaO_(2)、血清白蛋白(ABL)、简明精神状态量表(MMSE)评分、蒙特利尔认知评估量表(MoCA)评分、6MWT、30 s-STS及慢性肾衰竭生命质量量表(QLICD-CRF)评分明显高于对照组,焦虑自评量表(SAS)评分、抑郁自测量表(SDS)评分明显低于对照组,差异均有统计学意义(P<0.05)。结论功能运动训练可显著提高血液透析治疗CKD患者的透析充分性,提高患者认知功能和运动能力,改善患者焦虑抑郁情绪,并提升其生活质量。
Objective To observe the application efficacy of functional exercise training in the treatment of patients with chronic kidney disease(CKD).Methods A total of 60 patients with CKD diagnosed and treated in Qinhuangdao Hospital of Traditional Chinese Medicine from June 2019 to June 2020 were selected as research subjects,and they were divided into the control group(n=30)and the exercise group(n=30)according to the random number table method.Patients in the control group were treated with conventional hemodialysis,while patients in the exercise group were treated with functional exercise training intervention on the basis of treatment in the control group.Before treatment and 3 months after treatment,the dialysis adequacy,blood oxygen saturation(SaO_(2)),nutritional status,cognitive function,anxiety and depression degrees were compared between the two groups of patients.Besides,the 6-minute walking distance(6-minute walk test,6MWT)and the 30 s sit-to-stand test(30 s-STS)were tested,and the quality of life(QoL)was evaluated.Results After treatment,the single-compartment urea clearance rate(spKt/V),SaO_(2),serum albumin(ABL),scores of minimental state examination(MMSE)and Montreal cognitive assessment(MoCA),6MWT results,30 s-STS and scores of the QoL instruments for chronic diseases-chronic renal failure(QLICD-CRF)in the exercise group were obviously higher/better than those in the control group.The scores of self-rating anxiety scale(SAS)and selfrating depression scale(SDS)were obviously lower than those in the control group,all with statistically significant differences(P<0.05).Conclusion Functional exercise training can significantly upgrade dialysis adequacy of patients with CKD treated by hemodialysis,increase patients’cognitive function and exercise ability,relieve their anxiety and depression,and improve the QoL.
作者
朱丹
李连江
ZHU Dan;LI Lianjiang(Department of Nephropathy,Qinhuangdao Hospital of Traditional Chinese Medicine,Hebei,Qinhuangdao 066000,China)
出处
《中国医药科学》
2022年第17期9-13,共5页
China Medicine And Pharmacy
基金
河北省秦皇岛市科学技术研究与发展计划(201902A062)。
关键词
慢性肾脏病
功能运动
血液透析
认知功能
焦虑
抑郁
Chronic kidney disease
Functional exercise
Hemodialysis
Cognitive function
Anxiety
Depression
