摘要
目的探究与观察检测rasP21蛋白表达对鼻咽癌诊断的临床意义。方法选取本院收治的60例患者,将其作为临床研究对象,采用单克隆免疫检测法对60例鼻咽癌患者进行rasP21蛋白表达进行检测。结果 rasP21蛋白表达量与鼻咽癌患者的恶化程度呈正比的关系,鼻咽癌患者rasP21蛋白的阳性表达率为80%,正常人鼻咽膜rasP21蛋白表达阳性率为48%,两者差距达32%,P<0.05,表明不同临床分期患者rasP21表达差异有统计学意义,不同病理分期,随着恶化程度的增加,rasP21表达量上升。结论检测rasP21蛋白表达对鼻咽癌诊断有重要的临床意义,值得在临床上进一步地进行探讨和学习。
Objective To explore and observe the detection rasP21 protein expression of clinical significance in nasopharyngeal carcinoma diagnosis. Methods Sixty cases of patients were selected as clinical research objects in our hospital, monoclonal immunoassays was used for 60 patients to detect nasopharyngeal carcinoma rasP21 protein ex- pression. Results RasP21 protein expression quantity was proportional to the degree of deterioration in patients with nasopharyngeal carcinoma （NPC）, rasP21 protein positive expression rate in patients with nasopharyngeal carcinoma were 80%, normal nasopharyngeal rasP21 membrane protein expression were 48%, the gap was 32%. P 〈 0.05, it showed that different clinical stage with rasP21 expression difference was statistically significant, patients with different pathological stages, with the increasement of degradation degree, rasP21 expression increased. Conclusion To detect rasP21 protein expression in the diagnosis of nasopharyngeal carcinoma （NPC） has important clinical significance and is worth discussing and studying in clinic.
出处
《中国当代医药》
2013年第15期82-83,共2页
China Modern Medicine
关键词
RASP21蛋白
鼻咽癌
临床分期
临床意义
RasP21 protein
Nasopharyngeal carcinoma
Clinical stage
Clinical significance
