摘要
以多聚磷酸为催化剂,邻苯二胺和冰乙酸为反应物,在微波辐射下合成了2-甲基苯并咪唑。反应的最佳条件为:微波输出功率700W、间歇辐射时间3min、n(邻苯二胺):n(冰乙酸)=1:2.5时,产率可达84.6%。
2-methylbenzimidazole was synthesized by the reaction of o-phenylenediamine with acetic acid in the presence of polyphosphoric acid （PPA） as catalyst through microwave enhanced. The optimum conditions were as follows： microware power of 700W, microwave enhanced time of 3 min., the mole ratio of o-phenylenediamine to acetic acid of 1：2.5, the yield was 84.6%.
出处
《唐山师范学院学报》
2008年第5期39-40,共2页
Journal of Tangshan Normal University
基金
河北省教育厅自然科学项目(2006114)。
关键词
微波辐射
2-甲基苯并咪唑
合成
microwave irradiation
2-methyl benzimidazole
synthesis
