摘要
为探讨苯并咪唑类曼尼希碱的研究现状,系统查阅了近几年来苯并咪唑类曼尼希碱的合成及其在医药领域中的应用等文献,归纳总结了苯并咪唑类曼尼希碱不同的合成路径。重点介绍其在杀菌,镇痛及抗炎,抗病毒和驱虫方面的活性,并对该类化合物的绿色合成及其在医药领域中的应用前景进行了简单的概括,阐明苯并咪唑类曼尼希碱具有广泛的应用价值和经济价值。
Discussion of present research status of Benzimidazole Mannich bases was based on consulting the synthesis and effects of the Benzimidazole Mannich bases on medicine reported in literatures, the summary and induction indicated that Benzimidazole Mannich bases had different synthetic routes. The activities in the antibacterial, analgesic and anti-inflammatory, anti-viral and anthelmintic were expounded. The simple description of the green synthesis and application prospects of Benzimidazole Mannich used in medicine field was given. The research showed that Benzimidazole Mannich bases possessed extensive application value and economical value.
出处
《广州化工》
CAS
2015年第11期19-21,共3页
GuangZhou Chemical Industry
基金
广东轻院拔尖人才培养工程资助项目(2012A020603023)
广东轻院自然科学基金资助项目(KJ201301)
广东省建设科技思想库研究课题项目(2014GDSXK011)
关键词
苯并咪唑
曼尼希碱
合成
应用
Benzimidazole
Mannich base
synthesis
application
