摘要
目的:对中药复方小续命汤石油醚总提取物中的成分及有效成分进行鉴定。方法:在进行生物活性研究的基础上,采用 GC 和 GC-MS 法对中药复方小续命汤中的脂溶性成分进行了分离鉴定。结果:共分离出100多种成分,并鉴定了其中的大多数成分。根据各成分所在的部位,判断其为有效成分或无效成分。结论:中药复方小续命汤中脂溶性成分(石油醚总提取物成分)含有多种化合物,其中包括有效成分和无效成分,对这些有效成分的认识能更好地阐明中药复方的有效成分及作用机制。
Objective:To identify the total components and effective components in petroleum ether extracts of Xiaoxuming decoction. Methods: After the research on bioactivity effects, GC and GC - MS methods were used to identify the effective fatty - dissolved components of Xiaoxuming decoction. Results: More than 100 components in petroleum ether extracts of Xiaoxuming decoction were separated and most of them were identified. The effective components were judged by their activity. Conclusion:With the identification of the total components and effective components, we can better ascertain the effective compounds and their action mechanism.
出处
《药物分析杂志》
CAS
CSCD
北大核心
2006年第5期577-584,共8页
Chinese Journal of Pharmaceutical Analysis
基金
863计划创新药物和中药现代化重大专项(2002AA22343B)
国家自然科学基金(30171148)
关键词
中药复方
小续命汤
有效成分
GC—MS
traditional Chinese medicine compound prescriptions
Xiaoxuming decoction
effective compound
GC - MS