摘要
目的观察微生物检验在泌尿系统病原菌检测中的应用价值。方法将90例泌尿系统感染患者作为研究对象,均采集其尿液实施病原菌分离检验。观察单一病原菌以及混合病原菌感染率、单一泌尿系统感染以及混合泌尿系统感染患者主要的病原菌类型、主要病原菌对常用抗菌药物的敏感度。结果泌尿系统感染患者单一病原菌感染率为75.56%,比混合病原菌感染率24.44%更高。单一病原菌感染患者的主要病原菌类型为大肠埃希菌、屎肠球菌、粪肠球菌、铜绿假单胞菌、肺炎克雷伯菌,占比分别为41.18%、26.47%、10.29%、4.41%、17.65%;其中大肠埃希菌占比最高,铜绿假单胞菌最低。混合病原菌感染患者的主要病原菌类型为念珠菌、耐甲氧西林金黄色葡萄球菌、变形杆菌,占比分别为72.73%、22.73%、4.55%;其中念珠菌占比最高,变形杆菌最低。大肠埃希菌对抗菌药物敏感度占比最高的三种药物分别为阿米卡星、头孢哌酮/舒巴坦、亚胺培南;屎肠球菌对抗菌药敏感度占比最高的三种药物分别为利奈唑胺、替加环素、万古霉素;粪肠球菌对抗菌药物敏感度占比最高的三种药物分别为青霉素、氨苄西林、亚胺培南;铜绿假单胞菌对抗菌药物敏感度占比最高的三种药物分别为阿米卡星、头孢他啶、头孢吡肟;肺炎克雷伯菌对抗菌药物敏感度占比最高的三种药物分别为阿米卡星、亚胺培南、头孢吡肟;念珠菌对抗菌药物敏感度占比最高的两种药物分别为两性霉素B、伏立康唑;耐甲氧西林金黄色葡萄球菌对抗菌药物敏感度占比最高的两种药物分别为利奈唑胺、万古霉素;变形杆菌对抗菌药物敏感度占比最高的两种药物分别为氨苄西林、阿米卡星。结论对于泌尿系统感染患者,单一病原菌常见病原菌类型包括大肠埃希菌、屎肠球菌、粪肠球菌、铜绿假单胞菌、肺炎克雷伯菌,混合病原菌�
Objective To observe the application value of microbiological test in the detection of pathogenic bacteria in urinary system.Methods 90 patients with urinary system infection were taken as the study subjects,and their urine was collected and tested for pathogen isolation.The infection rate of single and mixed pathogens,the main types of pathogens in patients with single and mixed urinary system infection,and the sensitivity of main pathogens to commonly used antibiotics were observed.Results The infection rate of single pathogen was 75.56%,which was higher than 24.44%of mixed pathogen.The main pathogenic bacteria types in patients with single pathogen infection were Escherichia coli,Enterococcus faecium,Enterococcus faecalis,Pseudomonas aeruginosa and Klebsiella pneumoniae,accounting for 41.18%,26.47%,10.29%,4.41%and 17.65%respectively,among which Escherichia coli accounted for the highest proportion and Pseudomonas aeruginosa the lowest.The main pathogenic bacteria types in patients with mixed pathogen infection were Candida,Methicillin-resistant staphylococcus aureus and Bacillus proteus,accounting for 72.72%,22.72%and 4.56%respectively,among which candida accounted for the highest proportion and Bacillus proteus the lowest.The three most sensitive drugs of Escherichia coli were amikacin,cefoperazone/sulbactam,imipenem.The three most sensitive drugs of Enterococcus faecium were linezolid,tigacycline and vancomycin.The three most sensitive drugs of Enterococcus faecalis were penicillin,ampicillin and imipenem.The three most sensitive drugs of Pseudomonas aeruginosa were amikacin,ceftazidime,and cefepime.The three most sensitive drugs of Klebsiella pneumoniae were amikacin,imipenem and cefepim.The two most sensitive drugs of Candida were amphotericin B and voriconazole.The two most sensitive drugs of Methicillin-resistant staphylococcus aureus were linezolid and vancomycin.The two most sensitive drugs of Bacillus proteus were ampicillin and amikacin.Conclusion For patients with single urinary system infection,the
作者
王婷
任家琦
WANG Ting;REN Jia-qi(The Fourth People's Hospital of Liaocheng,Liaocheng 252000,China)
出处
《中国现代药物应用》
2024年第8期29-32,共4页
Chinese Journal of Modern Drug Application
关键词
微生物检验
泌尿系统感染
病原菌
抗菌药物
Microbiological test
Urinary system
Pathogenic bacteria
Antibacterial drug
