摘要
目的分析ICU肺炎克雷伯菌感染危险因素,为制定预防措施提供依据。方法选取2019年11月—2020年12月收治的1453名患者,其中45例感染肺炎克雷伯菌。采用Logistic回归分析患者发生感染的危险因素。结果单因素分析年龄≥60岁、营养不良、入住ICU时间≥30天、抗菌药物总数≥3种、有创机械通气、呼吸系统疾病、侵入性操作、终末消毒残缺、标准预防落实不全的患者感染率更高(p<0.05)。多因素Logistic回归分析入住ICU时间、抗菌药物总数、侵入性操作、终末消毒残缺和标准预防落实不全为ICU肺炎克雷伯菌感染的独立影响因素(OR=5.272,4.475,7.062,7.320,6.141,p<0.05)。结论ICU中肺炎克雷伯菌感染为多种因素共同作用的结果,针对高风险因素制定并落实预防措施可以有效降低感染。
Objective To analyze the risk factors of Klebsiella pneumoniae infection in ICU so as to provide basis for formulating preventive measures.Methods A total of 1453 patients from November 2019 to December 2020 were selected,in which 45 cases were infected with Klebsiella pneumoniae.Logistic regression was used to analyze the risk factors for infection in patients.Results In univariate analysis,the infection rates of patients with age over 60 years old,malnutrition,ICU admission time over 30 days,total antibacterial drugs over 3 kinds,invasive mechanical ventilation,respiratory diseases,invasive operation,incomplete terminal disinfection and incomplete standard prevention were higher(p<0.05).Multivariate logistic regression analysis showed that ICU admission time,total number of antibacterial drugs,invasive operation,incomplete terminal disinfection and incomplete implementation of standard prevention were the independent influencing factors of Klebsiella pneumoniae infection in ICU(OR=5.272,4.475,7.062,7.320,6.141,p<0.05).Conclusion Klebsiella pneumoniae infection in ICU is the result of a combination of many factors.Developing and implementing preventive measures for high risk factors can effectively reduce the infection.
作者
黄可静
陈洁
陈晓青
潘子木
HUANG Ke-jing;CHEN Jie;CHEN Xiao-qing;PAN Zi-mu(The First Affiliated Hospital of Wenzhou Medical University)
出处
《医院管理论坛》
2022年第10期51-55,共5页
Hospital Management Forum
基金
浙江省医药卫生科技计划项目,编号:2021KY784。
