摘要
细胞焦亡是一种新发现的程序性细胞死亡方式,在肝癌中发挥着关键作用。故拟基于细胞焦亡的分子机制及其在肝癌发病机制中的作用进行深入分析,并结合中医药在调节焦亡肝癌发展过程中的作用进行探讨,以期为临床提供新的治疗思路。
Pyroptosis is a newly discovered mode of programmed cell death that plays a key role in hepatocellular carcinoma.This paper probes into the molecular mechanism of pyroptosis and its role in the pathogenesis of hepatocellular carcinoma,and discusses the role of traditional Chinese medicine in regulating pyroptosis to curb the development of hepatocellular carcinoma,with a view to providing new therapeutic ideas for clinical practice.
作者
杨润瑞
王勇
段柳剑
柯尊丽
YANG Runrui;WANG Yong;DUAN Liujian;KE Zunli(Guizhou University of Traditional Chinese Medicine,Guiyang 550000,China;Key Laboratory of Synthetic Biology,CAS Center for Excellence in Molecular Plant Sciences,Chinese Academy of Sciences,Shanghai 200000,China)
出处
《世界中医药》
CAS
2023年第20期2983-2987,共5页
World Chinese Medicine
基金
国家自然科学基金地区基金项目(82060797)
贵州省科技创新人才团队(黔科合平台人才[2020]5010)
贵州省发改委工程研究中心建设项目(黔发改高技[2020]896号)。
关键词
肝癌
肿瘤
炎症小体
细胞死亡
细胞焦亡
中医药
分子机制
研究进展
Hepatocellular carcinoma
Tumor
Inflammasome
Cell death
Pyroptosis
Traditional Chinese medicine
Molecular mechanism
Research progress
