摘要
目的探究高频超声检测颈动脉斑块与冠心病的相关性,为临床早期诊断冠心病提供依据。方法选择新疆医科大学第一附属医院2019年10月至2021年4月确诊的冠心病患者70例为病变组和健康志愿者70例为对照组。所有患者均进行颈动脉超声检查,将对照组与病变组基线资料、颈动脉斑块数目、血管内中膜厚度、颈动脉硬化等级评分、斑块Crouse积分、病理学分型等资料进行对比,以冠脉造影为诊断金标准,评估颈动脉斑块超声参数颈动脉内中膜厚度(IMT)对冠心病的诊断价值。结果同对照组相比,病变组的糖尿病例数、总胆固醇(TC)水平、吸烟率、颈动脉斑块数、IMT、颈动脉硬化等级评分、斑块Crouse积分均明显高于对照组,差异有统计学意义(P<0.05)。病变组检出硬斑块11例,软斑块40例,混合斑块19例,均高于对照组(软斑块3例,硬斑块2例,混合斑块2例),两组各斑块检出率比较差异均具有统计学意义(P<0.05)。IMT诊断冠心病的灵敏度为92.42%(64/70),特异度为88.57%(62/70),阳性预测值为88.88%(64/72),阴性预测值为91.17%(62/68),准确度为90%(126/140)。病变组中71~80岁IMT增厚率、斑块形成率最高,61~70岁次之,51~60岁最低。结论颈动脉斑块的形成与冠心病发生有着密切的关系,采用高频超声能够对冠状动脉病变起到预测作用,为冠心病的早期诊断提供可靠依据,具有较高的临床价值。
Objective To explore the correlation between carotid plaque and coronary heart disease(CHD)detected by high-frequency ultrasound,and to provide basis for early clinical diagnosis of CHD.Methods 70 patients with coronary heart disease diagnosed from October 2019 to April 2021 in the hospital were selected as the pathological group,and 70 healthy volunteers were regardedas the control group.All patients were examined by carotid ultrasound.The baseline data,carotid plaque number,intima-media thickness,carotid atherosclerosis grade score,plaque Crouse score,pathological classification and other data of the control group and the lesion group were compared.Coronary angiography was used as the diagnostic gold standard to evaluate the diagnostic value of carotid pla-que ultrasound parameter carotid intima-media thickness(IMT)for coronary heart disease.Results compared with the control group,the number of patients with diabetes,total cholesterol(TC),smoking rate,carotid plaque number,IMT,carotid atherosclerosis grade score and plaque crouse score in the lesion group were significantly higher than those in the control group(P<0.05).There were 11 cases of hard plaque,40 cases of soft plaque and 19 cases of mixed plaque in the lesion group,which were higher than those in the control group(3 cases of soft plaque,2 cases of hard plaque and 2 cases of mixed plaque).The difference in the detection rates of each plaque between the two groups were statistically significant(P<0.05).The sensitivity,specificity,positive predictive value,negative predictive value and accuracy of IMT in diagnosing coronary heart disease were 92.42%(64/70),88.57%(62/70),88.88%(64/72),91.17%(62/68)and 90%(126/140)respectively.IMT thickening rate and plaque formation rate were the highest in 71~80 years old patients,followed by 61~70 years old patients and the lowest in 51~60 years old patients.Conclusion The formation of carotid plaque is closely related to the occurrence of coronary heart disease.High frequency ultrasound can predict coronary artery dis
作者
马婷
穆玉明
关丽娜
MA Ting;MU Yuming;GUAN Lina(Department of Cardiac Ultrasound Diagnosis,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)
出处
《新疆医科大学学报》
CAS
2022年第11期1306-1310,共5页
Journal of Xinjiang Medical University
基金
新疆维吾尔自治区自然科学基金-青年科学基金(2022D01C254)。
关键词
高频超声
颈动脉斑块
冠状动脉病变
high-frequency ultrasound
carotid plaque
coronary artery disease
