摘要
目的:建立一种适用于英国的新型心血管风险评分(QRISK)模型,并验证其相对于已确立的Framingham心血管疾病评估系统及新近建立的Scottish评分(ASSIGN)的效能。设计:利用自全科诊所常规收集的数据进行前瞻性开放性队列研究。地点:将数据归纳入QRESEARCH数据库的英国诊所。
Objective: To derive a new cardiovascular disease risk score(QRISK) for the United Kingdom and to validate its performance against the established Framingham cardiovascular disease algorithm and a newly developed Scottish score(ASSIGN). Design: Prospective open cohort study using routinely collected data from general practice. Setting: UK practices contributing to the QRESEARCH database. Participants: The derivation cohort consisted of 1.28 million patients, aged 35- 74 years, registered at 318 practices be...