摘要
目的分析在对妊娠期糖尿病患者进行门冬胰岛素注射液、运动疗法共同治疗的效果。方法70例妊娠期糖尿病患者,结合组内随机性抽选的方式分为对照组和观察组,每组35例。对照组患者选择生物合成人胰岛素进行治疗,观察组则需要按照运动疗法与门冬胰岛素注射液相结合的方式进行治疗。比较两组患者治疗前后血糖、糖化血红蛋白水平以及妊娠结局情况、新生儿情况。结果治疗后,观察组空腹血糖(6.25±1.24)mmol/L、餐后2 h血糖(7.03±1.15)mmol/L、糖化血红蛋白(5.05±1.41)%均低于对照组的(7.64±1.13)mmol/L、(8.84±1.04)mmol/L、(7.15±1.32)%,差异均具有统计学意义(t=4.902、6.906、6.432,P=0.000、0.000、0.000<0.05)。观察组中2例患者进行剖宫产,1例出现产后出血,2例出现产后感染;对照组则有7例接受剖宫产,5例出现产后出血,4例出现产后感染。观察组不良妊娠结局发生率14.29%低于对照组的45.71%,差异具有统计学意义(P<0.05)。观察组新生儿不良结局发生率8.57%低于对照组的28.57%,差异具有统计学意义(χ^(2)=4.629,P=0.031<0.05)。结论妊娠期糖尿病患者按照运动疗法、门冬胰岛素注射液相结合的方式进行治疗,可以有效提升对患者的治疗效果,改善患者血糖水平以及妊娠结局,并保障新生儿健康。
Objective To analyze the effect of insulin aspart injection combined with exercise therapy on gestational diabetes mellitus.Methods A total of 70 patients with gestational diabetes were randomly divided into control group and observation group,with 35 cases in each group.Patients in the control group were treated with biosynthetic human insulin,while patients in the observation group was treated with exercise therapy and insulin aspart injection.Comparison was made on the blood glucose,glycosylated hemoglobin levels before and after treatment,pregnancy outcome,and newborn status between the two groups.Results After treatment,the fasting blood glucose(6.25±1.24)mmol/L,2 h postprandial blood glucose(7.03±1.15)mmol/L and glycosylated hemoglobin(5.05±1.41)%in the observation group were lower than(7.64±1.13)mmol/L,(8.84±1.04)mmol/L and(7.15±1.32)%in the control group,and the differences were all statistically significant(t=4.902,6.906,6.432;P=0.000,0.000,0.000<0.05).In the observation group,2 patients underwent cesarean delivery,1 patient had postpartum hemorrhage,and 2 patients had postpartum infection;in the control group,7 patients underwent cesarean section,5 patients had postpartum hemorrhage,and 4 patients had postpartum infection.The incidence of adverse pregnancy outcomes 14.29%in the observation group was lower than 45.71%in the control group,and the difference was statistically significant(P<0.05).The incidence of adverse neonatal outcome 8.57%in the observation group was lower than 28.57%in the control group,and the difference was statistically significant(χ^(2)=4.629,P=0.031<0.05).Conclusion In the treatment of patients with gestational diabetes mellitus,the combination of exercise therapy and insulin aspart injection can effectively improve the therapeutic effect,blood glucose level and pregnancy outcome of patients,and ensure the health of newborns.
作者
王娜
WANG Na(Dalian Women’s and Children’s Medical Center,Dalian 116000,China)
出处
《中国实用医药》
2021年第27期111-113,共3页
China Practical Medicine
关键词
门冬胰岛素注射液
运动疗法
妊娠期糖尿病
Insulin aspart injection
Exercise therapy
Gestational diabetes mellitus
