摘要
目的探析妊娠期糖尿病患者应用门冬胰岛素注射液联合饮食运动疗法对不良妊娠结局的控制作用。方法选取106例妊娠期糖尿病患者随机分为甲组(53例,门冬胰岛素注射液+饮食运动疗法)与乙组(53例,二甲双胍+饮食运动疗法)。对比两组患者治疗前、后血糖控制情况、不良分娩结局和不良新生儿结局。结果治疗后,两组空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(HbA1c)水平均降低,且甲组明显低于乙组(P<0.05)。甲组的不良分娩结局总发生率及不良新生儿结局总发生率低于乙组(P<0.05)。结论妊娠期糖尿病应用门冬胰岛素注射液联合饮食运动疗法可改善患者血糖,减少不良妊娠结局。
Objective To investigate the control effect of insulin aspart injection combined with diet and exercise therapyon adverse pregnancy outcomes in patients with gestational diabetes mellitus. Methods A total of 106 patients withgestational diabetes mellitus were randomly divided into groupA （53 cases, insulin aspart injection ＋diet and exercisetherapy） and groupB （53 cases, metformin＋diet and exercise therapy）. The blood glucose control before and after treatment,adverse delivery outcomes and adverse neonatal outcomes of the two groups were compared. Results After treatment, thelevels of fasting blood glucose （FBG）, 2h postprandial blood glucose （2h PBG）, and glycosylated hemoglobin （HbA1c）decreased in the two groups, and those of the group A were significantly lower than the groupB（P〈0.05）. The total incidenceof adverse delivery outcomes and the overall incidence of adverse neonatal outcomes in the group A were lower than those inthe groupB （P〈0.05）. Conclusion Insulin aspart injection combined with diet and exercise therapy in patients withgestational diabetes mellitus can improve the control of blood glucose and reduce the adverse pregnancy outcomes.
作者
王剑如
王超
WANG Jian-ru;WANG Chao(Chencang Hospital of Baoji,Baoji 721300,China)
出处
《临床医学研究与实践》
2018年第25期136-137,共2页
Clinical Research and Practice
关键词
门冬胰岛素注射液
饮食运动疗法
妊娠期糖尿病
不良妊娠结局
insulin aspart injection
diet and exercise therapy
gestational diabetes mellitus
adverse pregnancyoutcomes
