摘要
痛风属于代谢性风湿病范畴,主要临床表现为关节的红、肿、热、痛和活动受限,目前西医治疗痛风虽取得一定疗效,但存在费用高昂、容易诱发肝肾损伤等不足。因此从中药中寻找、开发防治痛风的新药将成为痛风防治工作的研究热点。土茯苓因具有除湿、解毒,通利关节的作用,成为临床上治疗痛风的常用药。笔者通过整理国内外相关文献,对土茯苓防治痛风的作用机制进行了综述。结果发现土茯苓通过降尿酸、抗炎镇痛、保护肝肾等对痛风发挥治疗作用,且毒副作用小,具有深入研究价值。
Gout belongs to the category of metabolic rheumatic diseases,which is characterized by red,swollen,heat,painful and limited movement of the joints.At present,western medicine has certain curative effects on gout,but it is expensive andis easy to damage the liver and kidneys.Therefore,the search and development of new drugs for gout prevention and treatment will become a research hotspot.Tufingling(Rhizoma Smilacis Glabrae)has become a commonly used drug in the treatment of gout,because of its functions of eliminating dampness,detoxification and joint mobilization.Therefore,were viewed the mechanisms of Tufingling(Rhizoma Smilacis Glabrae)in preventing and treating gout by researching the relevant literature at home and abroad.Ultimately,we found that Tufingling(Rhizoma Smilacis Glabrae)has a therapeutic effect on gout by reducing uric acid,being antipyretic,anti-inflammatory,having analgesic effects,preventing formation of uratecrystals,hepatoprotective and nephroprotective.So far with few side effects,it can be used for further research.
作者
王特
张晓宇
张薇
杨小又
李兆福
WANG Te;ZHANG Xiaoyu;ZHANG Wei;YANG Xiaoyou;LI Zhaofu(Yunnan University of Traditional Chinese Medicine,Kunming 650500,Yunnan,China;The First Affiliated Hospital of Yunnan University of Traditional Chinese Medicine,Kunming 650021,Yunnan,China)
出处
《辽宁中医杂志》
CAS
2021年第1期215-217,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81760868)
云南省应用基础研究重点项目(2016FA037)
云南省高层次中医药人才(领军人才)培养项目
云南省中青年学术技术带头人后备人才培养项目(2015HB052)。
关键词
土茯苓
痛风
作用机制
综述
Tufingling(Rhizoma Smilacis Glabrae)
gout
mechanism
review
