摘要
目的了解南通市0~6岁儿童血清维生素A和维生素E水平,为儿童科学补充维生素A、维生素E及有关部门预防相关疾病提供参考依据。方法采用高效液相色谱法(HPLC)检测2017年1月至2018年12月于南通市妇幼保健院体检的0~6岁3016名儿童血清维生素A、维生素E水平,比较不同性别及年龄组的维生素A和维生素E正常及缺乏情况。结果南通市0~6岁儿童血清维生素A平均浓度为(0.30±0.07)mg/L,维生素E平均浓度为(10.48±2.55)mg/L,男童均显著低于女童(t值分别为-3.534、-7.594,均P<0.05),不同年龄段儿童血清维生素A、E水平不同,差异有统计学意义(F值分别为3.386、51.818,均P<0.05),两两比较发现维生素A水平从高到低依次为3~≤6岁、1~≤3岁、0~≤1岁,维生素E水平从高到低依次为1~≤3岁、0~≤1岁、3~≤6岁;维生素A正常、不足、缺乏的比例依次为51.1%、43.8%、5.1%,维生素E正常、不足、缺乏的比例依次为93.7%、5.6%、0.7%,不同性别、年龄组儿童维生素A、E分布情况不同(均P<0.05)。结论南通市0~6岁儿童维生素A不足和缺乏的比例较高,营养状况较差,应加强监测,以预防相关疾病;维生素E不足和缺乏比例较低,营养状况较好。
Objective To investigate serum levels of vitamin A and vitamin E of children aged 0~6 years in Nantong city,and to provide basis for supplementing vitamin A and vitamin E for the children and preventing the related diseases for relating departments.Methods High-performance liquid chromatography(HPLC)was used to detect the serum levels of vitamin A and vitamin E of 3016 children aged 0~6 years who received regular physical examination in The Affiliated Nantong Maternity and Child Health Hospital of Nantong University from January 2017 to December 2018.The serum levels of vitamin A and vitamin E of the children in different genders and age groups were compared.Results The average serum level of vitamin A of the children aged 0~6 years in Nantong was 0.30±0.07 mg/L,and their average serum level of vitamin E was 10.48±2.55 mg/L.The average serum levels of vitamin A and vitamin E of the boys were significantly lower than those of the girls(t=-3.534 and-7.594 respectively,both P<0.05).There were significant differences in serum levels of vitamin A and E of the children among different age groups(F=3.386 and 51.818 respectively,both P<0.05).Two-two comparison shown that vitamin A level from high to low was in 3~≤6 years old group,1~≤3 years old group,0~≤1 year old group in order,and vitamin E level from high to low was in 1~≤3 years old group,0~≤1 year old group,3~≤6 years old group;the proportions of normal,insufficient and deficient vitamin A level was 51.1%,43.8%and 5.1%respectively,and the proportions of normal,insufficient and deficient vitamin E was 93.7%,5.6%and 0.7%respectively.The distributions of serum levels of vitamin A and vitamin E in different genders and age groups were different(all P<0.05).Conclusion The proportions of vitamin A insufficiency and deficiency in the children aged 0~6 years in Nantong are high,and their nutritional status is poor.Therefore,monitoring should be strengthened to prevent development of related diseases.While the proportions of vitamin E insufficiency and deficie
作者
许占斌
倪钰飞
徐小晶
江琤琤
顾瑞娟
XU Zhanbin;NI Yufei;XU Xiaojing;JIANG Chengcheng;GU Ruijuan(Department of Child Health,The Affiliated Maternity and Child Health Hospital of Nantong University,Jiangsu Nantong 226018,China)
出处
《中国妇幼健康研究》
2020年第11期1541-1544,共4页
Chinese Journal of Woman and Child Health Research
基金
国家卫生计生委医药卫生科技项目(W2016EWJS09)
南通市妇幼健康专科联盟(TFM201908)。
