摘要
目的调查结肠息肉临床发病特点、影响因素,提高人们对结肠息肉的认识,做好结肠息肉筛查,更好地防治结肠息肉。方法选取2017年1月-2019年6月上海中医药大学附属曙光医院收治的180例经临床诊断为结肠息肉患者作为观察组,另选取同期于医院健康体检的正常人群180例为对照组,比较两组研究对象的年龄、性别构成和血生化指标等。结果观察组男性比例为66.67%,明显高于对照组(χ^2=4.68,P=0.03);观察组平均年龄为(62.57±4.81)岁,明显大于对照组(50.93±5.24)岁(t=21.96,P=0.00)。观察组幽门螺杆菌(HP)感染率、吸烟史率明显高于对照组,观察组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)和CEA水平明显高于对照组,高密度脂蛋白(HDL)水平明显低于对照组。观察组2型糖尿病、高血压患病、肿瘤家族史和胆囊切除率明显高于对照组。二元logistic回归分析发现,年龄、HP感染、吸烟、高血压、TG水平和CEA水平为结肠息肉发病的独立性危险因素。结论结肠息肉发病因素较多,如年龄大、HP感染及TG水平高等,所以临床要重视结肠癌发病高危因素,加强宣传和引导,以便更好地指导人们合理防治结肠息肉。
OBJECTIVE To investigate the incidence of colon polyps clinical characteristics,influencing factors,to raise awareness of colon polyps,colon polyps do the screening,better prevention and treatment of colon polyps.METHODS January 2017-June 2019,180 cases of clinically diagnosed as colon polyps study observation group,selected 180 cases in another hospital in the same period of healthy normal population study as the control group.Comparison of two groups were age,gender,blood biochemical indicators were given.RESULTS There were male ratio was 66.67%,was significantly higher than 55.56%,χ^2=4.68,P=0.03;mean age was observed(62.57±4.81)years,significantly greater than in the control group(50.93±5.24)years,t=21.96,P=0.00.Observation group of Helicobacter pylori(HP)infection,smoking history was significantly higher in the observation group total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL),CEA levels were significantly higher in high density lipoprotein(HDL)levels were significantly lower than the control group.Observation group type 2 diabetes,hypertension,family history of cancer,cholecystectomy was significantly higher,Multivariate Logistic regression analysis found that age,HP infection,smoking,high blood pressure,TG level,CEA level of incidence of colon polyps independent risk factor.CONCLUSION The incidence of colon polyps many factors,such as older,HP infection and TG levels higher,so should pay attention to clinical risk factors for colon cancer,strengthen propaganda and guidance,in order to better guide prevention and treatment of colon polyps reasonable people.
作者
宋灵敏
王坚
SONG Ling-Min;WANG Jian(Shuguang Hospital Affiliated to Shanghai University of traditional Chinese Medicine,Shanghai,200021,China)
出处
《中国初级卫生保健》
2020年第5期106-108,共3页
Chinese Primary Health Care
关键词
结肠息肉
因素
高血压
总胆固醇
幽门螺杆菌
甘油三酯
colon polyps
factors
high blood pressure
total cholesterol
helicobacter pylori
triglycerides
