摘要
目的:探讨扶正抑癌汤联合腹腔镜辅助小切口根治手术治疗胃癌的效果及对患者免疫功能的影响。方法:选择80例胃癌患者,按随机数字表法分为观察组和对照组各40例。对照组行腹腔镜辅助小切口根治手术治疗,观察组予以扶正抑癌汤联合腹腔镜辅助小切口根治术手术治疗,比较2组患者临床疗效及免疫功能。结果:治疗前,2组中医症状评分比较,差异无统计学意义(P>0.05)。治疗后,2组中医症状评分较治疗前下降(P<0.05),且观察组中医症状评分低于对照组(P<0.05)。治疗前,2组癌胚抗原(CEA)、糖类抗原199 (CA199)、糖类抗原125 (CA125)水平比较,差异无统计学意义(P>0.05)。治疗后,2组CEA、CA199、CA125水平较治疗前下降(P<0.05),且观察组CEA、CA199、CA125水平低于对照组(P<0.05)。治疗前,2组CD4^+、CD8^+、CD4^+/CD8^+水平比较,差异无统计学意义(P>0.05)。治疗后,2组CD4^+、CD8^+、CD4^+/CD8^+水平较治疗前升高(P<0.05),且观察组CD4^+、CD8^+、CD4^+/CD8^+水平高于对照组(P<0.05)。结论:扶正抑癌汤联合腹腔镜辅助小切口根治手术治疗胃癌效果显著,可有效降低相关肿瘤标志物水平,并改善患者免疫功能。
Objective: To investigate the effect of Fuzheng yiai tang combined with laparoscopy assisted small incision radical operation on gastric cancer and the effect on the immune function of patients. Methods:Selected 80 cases of patients with gastric cancer and divided them into the observation group and the control group according to the random number table,with 40 cases in each group. The control group was treated with laparoscopy assisted small incision radical operation and the observation group was given Fuzheng yiai tang combined with laparoscopy assisted small incision radical operation. Compared the clinical effect and immune function of patients in the two groups. Results:Before treatment,there was no significant difference being found in the comparison of Chinese medicine symptom scores in the two groups(P>0.05). After treatment,the Chinese medicine symptom scores in the two groups were decreased when compared with those before treatment(P<0.05),and the Chinese medicine symptom scores in the observation group were lower than those in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of the levels of carcinoembryonic antigen(CEA), carbohydrate antigen 199(CA199) and carbohydrate antigen 125(CA125) in the two groups(P>0.05). After treatment, the levels of CEA, CA199 and CA125 in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of CEA,CA199 and CA125 in the observation group were lower than those in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of the levels of CD4^+,CD8^+,CD4^+/CD8^+ in the two groups(P>0.05). After treatment,the levels of CD4^+,CD8^+,CD4^+/CD8^+ in the two groups were increased when compared with those before treatment(P<0.05),and the levels of CD4^+,CD8^+,CD4^+/CD8^+ in the observation group were higher than those in the control group(P<0.05). Conclusion: The application of Fuzheng yiai tang combined with laparoscopy assiste
作者
俞国法
蔡国英
YU Guofa;CAI Guoying
出处
《新中医》
CAS
2020年第4期121-124,共4页
New Chinese Medicine
