摘要
目的探讨全身麻醉(全麻)维持期全凭七氟烷吸入麻醉对老年患者术后早期睡眠质量的影响。方法选择该院2017年12月至2018年12月拟择期全麻下行手术治疗的老年患者100例,美国麻醉医师分级(ASA)Ⅰ~Ⅲ级。按随机数字表法分为A组和B组,每组50例。A组采用全麻维持期全凭丙泊酚泵注;B组采用全麻维持期七氟烷吸入。连续检测患者手术当晚19:00至术后第2天07:00共12 h的脑电双频指数(BIS)得出总睡眠时间和觉醒时间,记录术后第2天07:00患者匹兹堡睡眠质量指数(PSQI)评分,并每隔2 h记录患者平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO2)、呼吸频率(RR)。结果2组患者手术当晚19:00至术后第2天7:00,每隔2 h的MAP、HR、SpO2及RR比较,差异均无统计学意义(P>0.05);与A组比较,B组患者总睡眠时间显著延长,PSQI评分明显降低(且均值低于6分),差异均有统计学意义(P<0.05)。结论全麻维持期全凭七氟烷吸入能够延长老年患者术后早期总睡眠时间,且改善其睡眠质量。
Objective To investigate the effect of sevoflurane inhalation anesthesia on early postoperative sleep quality in elderly patients.Methods A total of 100 elderly patients with elective surgical treatment under general anesthesia in this hospital from December 2017 to December 2018 were selected,who were classified as gradeⅠ-Ⅲby American Society of Anesthesiologists.According to the random number table,all patients were divided into the group A and B,50 cases in each group.The group A adopted the propofol pump injection during the maintenance period of general anesthesia;the group B adopted the sevoflurane inhalation during the maintenance period of general anesthesia.The total sleep time and total waking time were measured by BIS for 12 h from 19:00 on the night of surgery to 07:00 on the second day after surgery,and the Pittsburgh sleep quality index(PSQI)score was recorded at 07:00 on the second day after surgery,and mean arterial pressure(MAP),heart rate(HR),pulse oxygen saturation(SpO2)and respiratory rate(RR)were recorded every 2 h.Results Comparison of MAP,HR,SpO2,RR every 2 h from 19:00 on the night of surgery to 07:00 on the second day after surgery between the two groups showed no statistically significant differences(P>0.05).Compared with the group A,the total sleep time of patients in the group B was significantly prolonged,the PSQI score was significantly reduced(the mean value<6 points),and the differences were statistically significant(P<0.05).Conclusion Sevoflurane inhalation during the maintenance period of general anesthesia can prolong the total sleep time and improve sleep quality in the early postoperative period of elderly patients.
作者
贾文振
吴国荣
JIA Wenzhen;WU Guorong(Department of Anesthesia,Ningbo Huamei Hospital,University of Chinese Academy of Sciences,Ningbo,Zhejiang 315000,China)
出处
《现代医药卫生》
2020年第2期174-176,共3页
Journal of Modern Medicine & Health
基金
浙江省医学会临床科研基金项目(2017ZYC-A54)