摘要
目的探讨脂蛋白相关磷脂酶A2(LP-PLA2)、血管内皮生长因子(VEGF)和D-二聚体(D-Dimer)联合检测在急性脑梗死中的临床应用价值。方法选取116例急性脑梗死患者,按病情严重程度分为轻度组、中度组和重度组,另选同期健康体检者62例为健康对照组,分别检测血清LP-PLA2、VEGF、和D-Dimer的水平。结果急性脑梗死组上述3项实验室指标水平均显著高于健康对照组,差异有统计学意义(P <0. 01)。急性脑梗死患者的病情严重程度与LP-PLA2、VEGF和D-Dimer水平增高呈正相关,差异有统计学意义(P <0. 05)。结论血清LP-PLA2、VEGF、和血浆D-Dimer水平的联合检测对急性脑梗死患者的病情评估和预后分析有较大的临床应用价值。
Objective To study the combined detection value of Lipoprotein associated phospholipose A2( LP-PLA2),Vascular endothelial growth factor( VEGF) and D-dimer in the diagnosis of acute cerebral infarction. Methods 116 cases of acute cerebral infarction were divided into three groups: mild,moderate and severe,according to the severity of acute cerebral infarction. At the same time,62 cases of healthy people were selected as the control group. Combined detection of LP-PLA2,VEGF and D-dimer was conducted to diagnose the levels of acute cerebral infarction. Results The group of acute cerebral infarction showed higher value than that of the control group,with the differences statistically significant( P < 0. 05). The correlation between the severity of acute cerebral infarction and the value of combined detection showed close relationship,with the differences statistically significant( P < 0. 05). Conclusion The combined determination of LP-PLA2,VEGF and D-dimer show great clinical value for the illness evaluation and prognosis for acute cerebral infarction patients.
作者
焦淑静
JIAO Shu-jing(Clinical Laboratory, the Third People's Hospital of Shangqiu, Shangqiu, Henan 476000, China)
出处
《中国卫生检验杂志》
CAS
2019年第14期1742-1743,1747,共3页
Chinese Journal of Health Laboratory Technology
