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肝脏解毒酶对肉鸡生产性能、血液生化指标和肝脏黄曲霉毒素B_1残留的影响 被引量:2

Effect of Liver-detoxifizyme on Growth Performance, Serum Biochemical Parameters and Liver Aflatoxin B_1 Residues in Broilers
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摘要 本试验旨在研究肝脏解毒酶对肉鸡生产性能、血液指标和肝脏黄曲霉毒素B1(AFB1)残留的影响。选取1日龄AA肉仔鸡672只,随机分为7个处理组(A、B、C、D、E、F、G),每个处理8个重复,每个重复12只鸡。A、B、C组饲喂基础日粮+10%正常玉米,D、E、F、G组饲喂基础日粮+10%发霉玉米,B、E组以1 g/3L的比例在饮水中添加肝脏解毒酶,C、F组以1 g/5L的比例在饮水中添加肝脏解毒酶,G组以500 g/t的比例拌料加入肝脏解毒酶。试验期35 d。结果表明:发霉玉米能显著降低肉鸡前期的采食量(P<0.05),显著降低35日龄血液中的葡萄糖和白蛋白水平(P<0.05),显著增加35日龄肉鸡肝脏中的AFB1含量(P<0.05);添加解毒酶对正常玉米组的生产性能、血清生化指标和肝脏中AFB1含量均未产生显著影响(P>0.05);添加解毒酶能提高发霉玉米组的生产性能,增加21日龄的血液中血糖、总蛋白和白蛋白含量(0.05<P<0.10),显著降低肝脏中AFB1含量(P<0.05);饮水添加高剂量解毒酶(1 g/3L)的效果要好于饮水低剂量(1 g/5L)添加和拌料添加(500 g/t)。因此,当饲粮受到霉菌毒素污染或有潜在污染威胁时,推荐在肉鸡饮水中以1 g/3L的剂量添加肝脏解毒酶。 This experiment was conducted to investigate the effects of the liver-detoxifizyme on growth performance,serum biochemical parameters and the liver Aflatoxin B1(AFB1)residues in broilers.A total of 672 one-day-old AA broilers were randomly divided into 7 treatments(A,B,C,D,E,F,G)with 8 replicates of 12 broilers.Groups of A,B and C were fed basal diet with 10%extra normal corn.Groups of D,E,F and G were fed basal diet with 10%extra moldy corn.Groups of B and E were treated with the liver-detoxifizyme in drinking water by 1g/3L.Groups of C and F were treated with the liverdetoxifizyme in drinking water by 1g/5L.Group G were fed diet supplemented with 500g/t liver-detoxifizyme.The results were as follows:①the moldy corn significantly decreased average daily feed intake at the early period(P<0.05).The changed values were found in average body weight gain(P=0.0767)and the ratio of feed to body weight gain(P=0.0519).The liver AFB1 residue was increased(0.05<P<0.10).②No significant effect was found on the detected parameters in normal corn groups with liver-detoxifizyme(P>0.05).③In moldy corn groups,liver-detoxifizyme improved growth performance and increased the serum GLU,TP and ALB levels(0.05<P<0.10);the residues of AFB1 in liver were significantly decreased by liver-detoxifizyme(P<0.05).The detoxicating effects of high dose in drinking water(1g/3L)were better than low dosage treatment(1g/5L)and diet added treatment(500g/t).In conclusion,it is recommended to add liver-detoxifizyme at a dose of 1g/3L in drinking water when the diets were contaminated with mycotoxins or have potential contamination.
作者 郝洋洋 郭海岩 刘刚 张帅 王少琨 周华金 王炎辉 王俊谦 钟光 鲍英慧 宋志刚 HAO Yang-yang;GUO Hai-yan;LIU Gang;ZHANG Shuai;WANG Shao-kun;ZHOU Hua-jin;WANG Yan-hui;WANG Jun-qian;ZHONG Guang;Bao Ying-hui;SONG Zhi-gang(College of Animal Science and Technology,Shandong Agricultural University,Shandong Tai’an 271018,China;Shandong Xianpuairui Science and Technology Co.,Ltd,Shandong Weifang 261501,China;Huanshan Group Co.,Ltd,Shandong Qingdao 266101,China)
出处 《中国畜牧杂志》 CAS 北大核心 2018年第7期101-106,共6页 Chinese Journal of Animal Science
基金 山东省现代农业产业技术体系家禽创新团队项目(SDAIT-11-08)
关键词 肝脏解毒酶 肉鸡 黄曲霉毒素 生产性能 血清生化指标 Liver-detoxifizyme Broiler Aflatoxin Growth performance Serum biochemical index
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  • 1阮萃才,梁远,刘宗河.山楂等12种中药对黄曲霉毒素B_1诱变效应的抑制[J].癌症,1989,8(1):29-31. 被引量:21
  • 2刘大岭,姚冬生,陈敏峰.真菌提取液对黄曲霉毒素解毒作用的研究[J].广东药学院学报,1995,11(2):92-94. 被引量:35
  • 3王爱莉,李晓斐.常用血生化指标检测在各种肝病诊断中的应用[J].实用肝脏病杂志,2007,10(1):43-44. 被引量:18
  • 4Massey T E,Stewart R K,Daniels J M,et al. Biochemical and molecular aspects of mammalian susceptibility to aflatoxin B1 carcinogenicity [C]//Proceedings of the Society for Experimental Biology and Medicine,1995,208:213-227. 被引量:1
  • 5Ellis E M,Judah D J,Neal G E,et al. An ethoxyquininducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldoketo reductases [J]. Nad Acad Sci USA, 1993,90 : 10350. 被引量:1
  • 6Klein P J,Van-Vleet T R,HaU J O,et al. Biochemical factors underlying the age-related sensitivity of turkeys to aflatoxin BI[J]. Comparative Biochemistry and Physiology PartC, 2002,132:193-201. 被引量:1
  • 7Susumu. The fate and acute toxicity of aflatoxin B1 in the mastomys and rat [J ]. Toxicant, 1998,1 ( 136 ) : 179-188. 被引量:1
  • 8Aravind K L,Patil V S,Ganpule S P,et ol. Efficacy of modified glucomannan to counteract mycotoxicosis in naturally contaminated feed on performance, serum biochemical and hematological parameters in boilers [J]. Poultry Science,2003,82: 570-576. 被引量:1
  • 9Hsieh D P H. Mode of action of mycotoxins[M]//Krogh P. Mycotoxins in Food. Cambridge:Academic Press,1987,149-176. 被引量:1
  • 10Wilson V L,Jones P A. Inhibition of DNA methylation by chemical carcinogens [J ]. Cell, 1983,32 : 239-246. 被引量:1

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