摘要
目的:确定梅毒患者血清RPR滴度神经梅毒的相关性。方法:2013年6月至2016年6月就诊的360例梅毒患者(合并HIV感染120例)行腰椎穿刺及神经梅毒相关检查。结果:240例非HIV感染患者中,神经梅毒确诊或疑似病例68例,阳性率28.33%。120例HIV感染患者中,神经梅毒确诊或疑似病例61例,阳性率50.83%。HIV感染组中血RPR滴度对数为1∶1,1∶2,1∶4,1∶8,1∶16,1∶32的患者中神经梅毒阳性率分别为0%,33.33%,40%,75%,75%,66.67%,非HIV感染组分别为10%,15.38%,32.14%,35.71%,50%,50%,两组中神经梅毒阳性率与血清滴度均呈线性相关(P<0.05)。结论:神经梅毒与血清RPR滴度相关,滴度越高,神经梅毒可能性越大。
Objective： To determine the correlation between the serum RPR titers and neurosyphilis.Methods： Three hundred and sixty patients with syphilis（ 120 with HIV） diagnosed from June 2013 to June2016 were treated with lumbar puncture,CSF test and serum RPR titers test. Results： Sixty eight（ 28.33%）and 61（ 50.83%） patients were confirmed or suspected as having neurosyphilis in 240 patients with non-HIV infection and 180 patients with HIV infection respectively. The neurosyphilis positivity rates of the RPR titers 1 ∶1,1 ∶2,1 ∶4,1 ∶8,1 ∶16,1 ∶32 in the patients with HIV-infection were 0%,33.33%,40%,75%,75%and 66.67% respectively,while in the patients with non-HIV infection the neurosyphilis positivity rates were10%,15.38%,32.14%,35.71%,50% and 50% respectively. The syphilis positivity rate was linearly correlated with the serum RPR level in the patients（ P〈0. 05）. Conclusion： The neurosyphilis positivity rate was correlated with the serum RPR titer and the higher the serum titers level is,the higher the risk of neurosyphilis will be.
作者
卢改会
普雄明
LU Caihui;PU Xiongming(Xinjiang Medical University, Urumqi 830031, China;The Xinjiang Uygur Autonomous Region People＇s Hospital, Urumqi 830001, China)
出处
《中国麻风皮肤病杂志》
2017年第10期577-579,591,共4页
China Journal of Leprosy and Skin Diseases
