摘要
目的:利用决策树模型评价盐酸羟考酮缓释片和硫酸吗啡缓释片治疗癌痛患者的成本-效果。方法:采用循证医学的方法搜集盐酸羟考酮缓释片与硫酸吗啡缓释片治疗癌痛的随机对照临床试验,进行Meta分析并得到相应的有效率及不良反应发生率,以决策树模型进行成本-效果分析。结果:癌痛患者使用盐酸羟考酮缓释片和硫酸吗啡缓释片治疗两周的成本-效果比分别为603.84、335.37,增量成本效果比为8003,敏感性分析后显示结果稳定。结论:硫酸吗啡缓释片治疗癌痛的成本-效果优于盐酸羟考酮缓释片。
Objective： Decision tree model was used to evaluate cost-effectiveness of sustained-release oxycodone and sustained-release morphine for treatment of cancer pain patients. Methods： Evidencebased medicine method was used to collect random clinical controlled trials for treatment of cancer pain with sustained-release oxycodone and sustained-release morphine. Meta analysis was performed to obtain effective rate and adverse effects rate, and cost-effectiveness analysis was performed with decision tree model. Results： After two weeks＇ treatment with sustained-release oxycodone and sustained-release morphine, cost-effectiveness ratio of the two groups were 603.84 and 335.37 respectively, incremental costeffectiveness ratio was 8003; sensitivity analysis showed that the results were stable. Conclusion： Cost effectiveness of sustained-release morphine for treatment of cancer pain was superior to that of sustainedrelease oxycodone.
出处
《中国疼痛医学杂志》
CAS
CSCD
2016年第6期448-453,共6页
Chinese Journal of Pain Medicine
基金
"十二五"国家科技支撑计划课题"安全合理用药评价和干预技术研究与应用"(2013BAI06B04)
