摘要
目的:探讨首发抑郁症患者瘦素、脂联素及抵抗素等血清脂肪因子的水平。方法:首发抑郁症患者60例纳入抑郁组,健康体检者40例纳入对照组,进行体脂参数及瘦素、脂联素和抵抗素水平的测定。结果:2组体脂参数差异无统计学意义(P>0.05)。抑郁组血浆瘦素、脂联素浓度显著低于对照组(P<0.01),抵抗素浓度差异无统计学意义(P>0.05);2组内女性的瘦素水平均明显高于同组男性(P<0.01),不同性别患者脂联素和抵抗素差异无统计学意义(P>0.05)。结论:首发抑郁症患者存在一定水平的瘦素和脂联素浓度异常。
Objective：The aim of this study is to investigate the serum levels of adipocytokines- leptin, adiponectin, and resistin in patients with first episode depression. Methods： Sixty patients with first episode depression （depres-sion group） and 40 healthy controls （control group） were enrolled. The serum levels of leptin, adiponectin, and re-sistin were measured in all the cases. Results： There was no significance in anthropometric parameters between the two groups （P〉0.05）. The serum levels of leptin and adiponectin in the depression group were significantly lower than those in the control group （P〈0.01） and there was no significantly difference in serum level of resistin between the two groups （P〉0.05）. The serum level of leptin of females was higher than that of males in the both groups （P〈0.01）. There were no difference in the serum levels of adiponectin and resistin between female and male cases in the both groups （P〉0.05）. Conclusion： The serum levels of leptin and adiponectin in patients with first episode depres-sion are usually abnormal.
出处
《神经损伤与功能重建》
2015年第5期416-417,共2页
Neural Injury and Functional Reconstruction
基金
华中科技大学自主创新基金(No.2012QN048)
"宏源.力复君安杯"青年医师临床科研基金资助项目
关键词
抑郁症
瘦素
脂联素
抵抗素
depression
leptin
adiponectin
resistin
