摘要
心肌梗死是一种高致残率和致死率的疾病之一。其机制的初步探明已经为疾病的预防、诊断、药物靶点和治疗提供一些重要的信息,但更深层次的分子机制未明。该研究概述了动物模型与人类的心肌梗死组织蛋白质组学的研究进展,以及动物模型与人类的心肌梗死血清蛋白质组学的研究进展,并就心肌梗死蛋白质组学存在的问题以及发展方向进行探讨。
Myocardial infarction is a high morbidity and mortality disease. Its molecular mechanisms have initially provided important information for disease detection,diagnosis and rehabilitation, however,its mechanism is unknown at a deeper level This study summarized the research progress of the animal model with human myocardial infarction tissue proteomics. As well the animal model with human myocar- dial infarction blood serum proteomics and existing problems and development direction in myocardial infarction proteomics were discussed.
出处
《心血管病学进展》
CAS
2015年第5期616-619,共4页
Advances in Cardiovascular Diseases
基金
国家自然科学基金(81360535)
广西科学研究与技术开发计划项目(桂科合1347004-26)
广西自然科学基金课题(2013GXNSFAA019126)
关键词
心肌梗死
蛋白质组学
组织
血液
myocardial infarction
proteomies
tissue
blood
