摘要
目的探讨降钙素原在指导慢性阻塞性肺疾病急性加重期抗菌治疗中的价值。方法选取慢性阻塞性肺疾病急性加重期患者120例,随机均分为2组(n=60)。对照组采用常规治疗法,研究组采用降钙素原指导治疗,对比分析2组治疗情况与抗生素使用情况。结果研究组与对照组在临床有效率、复发率及住院病死率方面比较,差异均无统计学意义;研究组患者在抗生素使用率、抗生素使用费用、住院费用等方面均显著低于对照组,差异有统计学意义(P<0.05)。结论降钙素原在指导慢性阻塞性肺疾病急性加重期患者的抗菌治疗中能够有效降低患者的抗生素使用率,减少治疗费用与住院费用,具有一定的实际意义,值得临床推广应用。
Objective To investigate the guidance of procalcitonin in patients with chronic obstructive pulmonary disease with acute exacerbation of antimicrobial therapy Value. Methods 120 patients were admitted to our hospital for treatment of selected patients with chronic obstructive pulmonary disease with acute exacerbation, using completely random sampling method will be divided into study group and control groups, the control group using conventional therapy, the experimental group calcitonin elements of the original guide treatment, compared with the analysis of two groups of treatment with antibiotic use. Results Study group and the control group in clinical efficacy, relapse rate and in-hospital mortality was no significant difference in terms of meaningless statistically; study group of patients in terms of antibiotic usage, antibiotic usage fees, hospital costs, etc. were significantly lower than the control group, with significant differences, meaningful （P〈0.05） statistically. Conclusion Proealcitonin in guiding patients with chronic obstructive pulmonary disease in patients with acute exacerbation of antimicrobial therapy in patients can effectively reduce antibiotic usage, reduce the cost of treatment and hospitalization costs, has some practical significance, clinically widely.
出处
《当代医学》
2015年第13期112-113,共2页
Contemporary Medicine
关键词
降钙素原
慢性阻塞性肺疾病
急性加重期
抗菌治疗
Procalcitonin
Chronic obstructive pulmonary disease
Acute exacerbation
Antimicrobial therapy
