摘要
目的探讨在慢性阻塞性肺疾病患者的抗生素治疗中应用降钙素原检测指导治疗的临床价值。方法筛选出2018年5月至2019年5月于河南科技大学第三附属医院慢性阻塞性肺疾病患者100例,应用数字随机表将患者分为对照组与观察组,每组50例。对照组运用基础性的诊治方案,观察组运用降钙素原检测方式指导治疗。比较两组的临床诊治有效性、抗生素使用率、抗生素用药时间、抗生素用药费用、在院诊治时长、住院治疗费用。结果接受治疗后,两组的临床诊治有效性对照,差异未见统计学意义(P> 0.05)。较之对照组,观察组在抗生素使用率、抗生素用药时间、抗生素用药费用、在院诊治时长、住院治疗费用等方面更优(P <0.05)。结论在慢性阻塞性肺疾病患者的抗生素治疗中加入降钙素原检测方式指导治疗,诊治结局甚佳,能够有效缩减患者的抗生素用药时间及在院诊治时间,对抗生素使用率的降低具有积极意义,有助于患者获得良好预后。
Objective To investigate the clinical application value of adding procalcitonin detection method in the treatment of antibiotics in patients with chronic obstructive pulmonary disease( COPD). Methods A total of 100 patients with chronic obstructive pulmonary disease treated in the Third Affiliated Hospital of Henan University of Science and Technology from May 2018 to May 2019 were selected. The patients were divided into control group and observation group by digital random table,with50 cases in each group. The control group used a basic diagnosis and treatment plan,and the observation group used procalcitonin detection to guide treatment. The effectiveness of clinical diagnosis and treatment,antibiotic use rate,antibiotic medication time,antibiotic medication cost,hospital treatment duration,and hospitalization cost were compared. Results After treatment,there was no significant difference in the clinical effective rate of diagnosis and treatment between the two groups( P > 0. 05).Compared with the control group,the observation group was better in the use rate of antibiotics,the duration of antibiotic use,the cost of antibiotics,the length of time in hospital diagnosis and treatment,hospitalization costs and so on( P < 0. 05). Conclusions Adding procalcitonin test in the antibiotic treatment of patients with COPD can effectively reduce the antibiotic use time and hospital diagnosis and treatment time,and has positive significance in the reduction of antibiotic use rate,which helps patients to obtain good prognosis.
作者
王悦轩
李晓琳
吉瑜虹
Wang Yuexuan;Li Xiaolin;Ji Yuhong(Department of Respiratory Medicine,the Third Affiliated Hospital of Henan University of Science and Technology(Luoyang Dongfang Hospital),Luoyang 471003,China)
出处
《临床医学》
CAS
2020年第11期24-26,共3页
Clinical Medicine
关键词
降钙素原
慢性阻塞性肺疾病
抗生素
应用价值
Procalcitonin
Chronic obstructive pulmonary disease
Antibiotics
Application value
