摘要
目的探讨缺血性脑卒中患者血浆肾素水平与服用阿司匹林致消化道出血的关系。方法收集重庆医科大学附属第二医院神经内科2012年6月至2012年12月服用阿司匹林的缺血性脑卒中患者50例,按血浆肾素水平分为两组,低肾素组包含21例,高肾素组29例。随访1年,以出现呕血、黑便症状、大便隐血为阳性,内镜示消化道溃疡出血或者死亡为终点事件,比较两组患者消化道出血发生情况。结果低肾素组患者平均年龄高于高肾素组(P<0.05);低肾素组患者的血压较高肾素组高(P<0.05);低肾素组的消化道出血率较高肾素组高(P>0.05)。结论缺血性脑卒中者血浆肾素水平与服用阿司匹林后所致消化道出血无关。
Objective To investigate the relationship between plasma rennin levels in ischemic stroke patients and aspirin-in-duced gastrointestinal bleeding .Methods 50 ischemic stroke cases in neurology department of the Second Affiliated Hospital of Chongqing Medical University from June 2012 to December 2012 were collected and divided into 2 groups depended plasma rennin levels ：low rennin group and high rennin group .Low rennin group contained 21 cases and high rennin group containd 29 cases .Ap-pearance of haematemesis ,melena and fecal occult blood were considered as positive identification ,peptic ulcer bleeding in endoscope or death as the endpoint event in 1 year follow-up .Comparison of the incidence of gastrointestinal bleeding between 2 groups was made .Results The average age of patients in low rennin group was higher than that in high rennin group（P〈0 .05）;blood pres-sure of patients in low rennin group was higher than that of high rennin group（P〈0 .05）;gastrointestinal bleeding rate of low ren-nin group was higher than that of high rennin group（P〉0 .05） .Conclusion Different plasma rennin levels in ischemic stroke pa-tients may be unrelated to aspirin-induced gastrointestinal bleeding .
出处
《重庆医学》
CAS
CSCD
北大核心
2014年第29期3923-3925,共3页
Chongqing medicine
