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ACS患者入院早期血NT-proBNP、hs-CRP、UA水平与其再发心血管事件的关系 被引量:8

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摘要 目的探讨急性冠状动脉综合征(ACS)患者入院早期血浆氨基酸N未端脑钠肽原(NT-proBNP)、高敏C反应蛋白(hs-CRP)和血清尿酸(UA)水平与其再发心血管事件的关系。方法 ACS患者170例,入院后24 h内采集血标本,采用电化学发光免疫法检测血浆NT-proBNP,免疫透射比浊法检测血浆hs-CRP,尿酸酶法测定血清UA。患者均随访12个月,随访内容包括一般临床资料、心功能、主要不良心脏事件(MACE)。根据随访是否发生MACE分为MACE组及非MACE组,比较两组血浆NT-proBNP、hs-CRP和血清UA。结果 MACE组血浆NT-proBNP、hsCRP和血清UA值均高于非MACE组(P均<0.01);多因素Logistic回归分析显示,NT-proBNP、hs-CRP及UA均为ACS患者再发心血管事件的独立危险因子。结论血浆NT-proBNP、hs-CRP和血清UA水平与ACS患者再发心血管事件相关,可用于ACS的预后评估。
作者 王国敏
机构地区 琼海市人民医院
出处 《山东医药》 CAS 2014年第16期39-41,共3页 Shandong Medical Journal
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