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血清尿酸及C反应蛋白在急性冠状动脉综合征中的临床意义 被引量:2

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摘要 目的观察急性冠状动脉综合征(ACS)患者血清尿酸(UA)、超敏C反应蛋白(hs—CRP)的变化及其临床预后评估价值。方法选择经冠状动脉造影证实的冠心病患者122例(急性冠状动脉综合征组),同期冠状动脉造影正常的住院患者50例作为对照组。入院24h内分别测定血清尿酸、hs—CRP,出院3个月进行随访并行上述指标监测分析与再发心血管事件的关系。结果急性冠状动脉综合征组与对照组相比uA[(433±62.5)μmol/L与(298±47.6)mg/L,t=7.021,P〈0.05]及hs—CRP[(33.16±12.65)μmol/L与(8.59±2.35)mg/L,t=8.534,P〈0.01]明显升高且差异有统计学意义。相关分析显示血清尿酸及hs.CRP含量与ACS相关并与再发心血管疾病相关(r=0.387,P〈0.01)。结论uA和hs—CRP含量升高是ACS的危险因素,可作为ACS患者治疗中的监测指标,亦具有早期预防和再发心血管事件的预测价值。
出处 《中国综合临床》 2012年第3期270-271,共2页 Clinical Medicine of China
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