摘要
目的 探讨发病早期血清肌钙蛋白Ⅰ (cTnⅠ )水平在生心肌梗死 (AMI)预后判断方面的意义。方法 53例胸痛后 1 2h内入院的AMI患者在入院时及入院初取静脉血作血清cTnⅠ浓度检测 ,并对 44例存活出院患者中的 30例成功随访。按急性胸痛发作后的时间以及血清cTnⅠ浓度将患者分组 ,比较AMI早期血清cTnⅠ浓度与心脏事件的关系。结果 胸痛后 6h入院且血清cTnⅠ升高者 ,住院期间死亡、心脏事件发生率明显升高 ,长期随访心功能明显下降。胸痛后 6～ 1 2h入院者其入院时血清cTnⅠ均升高 ,超过90 μg/L者住院期间心脏事件发生率有增高趋势 ,入院时心功能明显下降。 结论 AMI 6h内血清cTnⅠ浓度升高对住院期间发生心脏事件的危险度有预测作用。
Objective To investigate the prognostic value of serum cardiac troponin I (cTnI) concentration in early phase of acute myocardial infarction(AMI). Methods Serum samples of 53 patients with confirmed AMI admitted within 12 hours after chest pain onset were collected at admission and the first hours after admission for measuring cTnI. We have successfully followed up 30 cases of the 44 survivals after hospitalization. All patients were grouped according to different admission time and cTnI level. Then we researched the relationship between cTnI concentration and cardiac events. Results Patients admitted within 6 hours after chest pain with elevated levels of cTnI had significantly higher incidence of cardiac death and cardiac events during hospitalization and worse cardiac function during long-term follow-up. All admission cTnI concentrations of patients admitted between 6 to12 hours were beyond cutoff value. Among these case, patients with serum cTnI concentrations higher than 90μg/L trended towards having higher incidence of cardiac events during hospitalization. Their cardiac function at admission was worse. Conclusion The elevated cTnI level of AMI patients admitted within 6 hours after chest pain has prognostic value of subsequent cardiac events risk during hospitalization.
出处
《中国煤炭工业医学杂志》
2003年第1期9-11,共3页
Chinese Journal of Coal Industry Medicine
关键词
急性心肌梗死
血清肌钙蛋白Ⅰ
心脏事件
AMI
acute myocardial infarction
serum troponin I concentration
cardiac event
early phase
