摘要
目的:了解某院药品不良反应(ADR)发生情况,为加强ADR监测、促进临床合理用药提供参考。方法:收集2012年351例ADR报告,对患者性别与年龄、给药途径、引起ADR的药品种类、累及器官和(或)系统、ADR的类型、报告人职业分布等项目进行统计、分析。结果:351例ADR主要涉及药品159种,其中抗菌药物引起的ADR最多,为128例次,占31.92%;静脉给药引起ADR最多,为213例,占60.68%;ADR累及器官和(或)系统及临床表现以消化系统损害最多,为183例次,占52.14%;报告人职业以医师为主,有74人,占91.17%。结论:ADR与多种因素有关,应做好监测,以促进合理用药。
OBJECTIVE：To investigate the adverse drug reactions （ADR） occurred in a hospital for reference of strengthening ADR monitoring and promoting collected in 2012 for statistical analysis with clinical rational use of drug. METHODS： 351 cases of ADR reports were regard to patients＇ gender and age, route of administration, types of drugs causing ADR, the organs and （or） system involved in ADR, ADR type, occupational distribution of the ADR reporters etc. RESULTS： Of the 351 ADR cases, 159 kinds of medicines were involved. The ADRs were mostly caused by antibiotics, with 128 cases, accounting for 31.92% ; the ADRs caused by intravenous administration took the lead with 213 cases, accounting for 60. 68% ; the organs and （or） systems involved in ADR and the clinical manifestations of the ADR were mainly lesion of digestive system with 183 cases, accounting for 52. 14% ; the occupation of the ADR reporters were mainly physicians with 74 people, accounting for 91.17%. CONCLUSION ： ADR and its monitoring were associated with a variety of factors, and it is important to strengthen ADR monitoring in order to promote rational use of drug.
出处
《中国医院用药评价与分析》
2013年第9期834-837,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
