摘要
目的：了解厦门市第三医院（以下简称＂我院＂）2014年药品不良反应（adverse drug reaction,ADR）报告的特点,为加强ADR监测和促进临床合理用药提供参考。方法：收集我院2014年的559例ADR报告,对报告总数、患者性别与年龄、涉及药品基本情况、ADR基本情况、报告人职业及科室分布等进行统计分析。结果：559例ADR报告中,男性与女性的比例为1.18∶1;15~44岁者最为突出,占46.15%;涉及怀疑药品200种,其中盐酸克林霉素氯化钠注射液的ADR报告例数最多,占20.23%;给药途径以静脉滴注为主,占52.90%;新的和严重的ADR报告占49.91%;ADR表现以胃肠系统损害最多,占28.43%;医师报告最多,占71.56%;报告科室以输液室最多,占23.97%。结论：我院应进一步加强行政管理和宣传教育,以提高ADR报告的数量与质量,促进临床安全、合理用药。
OBJECTIVE： To investigate the characteristics of adverse drug reaction（ ADR） reports in Xiamen Municipal Third Hospital（ hereinafter referred to as ＂our hospital ＂） in 2014,and to provide reference for the strengthening of ADR monitoring and promotion of rational drug use in clinic. METHODS： 559 cases of ADR reports in our hospital in 2014 were collected,statistical analysis was conducted on the total number of reports,patients＇ age and gender,general information of the involved drugs,general conditions of ADR and distribution of department and profession of reporters,etc. RESULTS： Of the 559 cases,ratio of male and female was 1. 18 ∶ 1; aged from 15-44 yearold took the most part,accounting for 46. 15%; 200 categories of suspected drugs were involved,among which clindamycin hydrochloride and sodium chloride injection dominated the first place,accounting for 20. 23%; the route of administration was mainly seen as intravenous drip,accounting for 52. 90%; new and severe ADR reports took up49. 91%. The main presentation of ADR was gastrointestinal system damage,accounting for 28. 43%; and ADR mostly reported by physicians（ 71. 56%） and infusion room（ 23. 97%）. CONCLUSIONS： Our hospital should further strengthen the administrative management and publicity and education,so as to improve the quantity and quality of the ADR reports,and promote the safe and rational drug use in clinic.
出处
《中国医院用药评价与分析》
2015年第12期1665-1669,共5页
Evaluation and Analysis of Drug-use in Hospitals of China
