摘要
目的研究纤溶酶对急性脑梗死急性期治疗的临床应用价值。方法选择2019年6月至2020年6月广东省高州市人民医院收治的148例急性脑梗死患者作为本次的研究对象,经过随机数字表法将其平均分为观察组和对照组,每组74例。观察组患者采用纤溶酶注射液和氯吡格雷进行治疗,对照组患者采用氯吡格雷进行常规治疗,统计治疗后观察组和对照组患者的治疗效果。结果观察组患者神经功能在治疗后明显优于对照组,观察组NIHSS评分治疗后低于对照组,差异有统计学意义(P<0.05);观察组患者日常生活活动能力在治疗后得到明显改善,改善程度优于对照组,Barthel指数高于对照组,差异有统计学意义(P<0.05);观察组的生活质量评分高于对照组,社交功能、心理健康、情感支持、肢体功能、生理功能评分均高于对照组,差异有统计学意义(P<0.05)。观察组患者术后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论纤溶酶联合氯吡格雷应用于急性脑梗死急性期治疗可以使患者获得更好的治疗效果,也能减少患者术后并发症的发生。
Objective To study the clinical application value of fibrinolytic enzyme in the treatment of acute cerebral infarction.Methods 148 patients with acute cerebral infarction admitted to our hospital from June 2019 to June 2020 were selected as the research objects,and were randomly divided into observation group and control group,with 74 cases in each group.Patients in the observation group were treated with plasmin injection and clopidogrel,while patients in the control group were treated with clopidogrel.The therapeutic effects of patients in the observation group and the control group were counted after treatment.Results The neurological function of the patients in the observation group was significantly better than that in the control group after treatment,and the NIHSS score in the observation group was lower than that in the control group after treatment,with statistical significance(P<0.05).After treatment,the activity of daily living in the observation group was significantly improved,the improvement degree was better than that in the control group,and Barthel index was higher than that in the control group,the difference was statistically significant(P<0.05).The scores of quality of life,social function,mental health,emotional support,limb function and physiological function in the observation group were higher than those in the control group(P<0.05).The incidence of postoperative complications in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Fibrinolytic enzyme combined with clopidogrel in the treatment of acute cerebral infarction can make patients get better therapeutic effect and reduce postoperative complications.
作者
吕江华
刘永林
LV Jiang-hua;LIU Yong-lin(Gaozhou People’s Hospital,Gaozhou,Guangdong 525200)
出处
《智慧健康》
2021年第23期123-125,共3页
Smart Healthcare
关键词
纤溶酶
急性脑梗死
急性期
治疗
Fibrinolytic enzyme
Acute cerebral infarction
Acute phase
Treatment
