摘要
目的:分析重组组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗早期急性脑梗死(ACI)的疗效及安全性。方法:2017年10月-2019年9月收治早期ACI患者78例,分为两组,各39例。观察组采取rt-PA静脉溶栓治疗,对照组采取奥扎格雷钠治疗。比较两组治疗效果。结果:观察组NIHSS评分及不良反应发生率明显低于对照组,总有效率及Barthel指数明显高于对照组,差异均有统计学意义(P<0.05)。结论:采用rt-PA静脉溶栓治疗早期ACI患者可改善患者预后,提高治疗效果,且安全性良好。
Objective:To analyze the efficacy and safety of rt-PA intravenous thrombolysis in the treatment of early ACI.Methods:From October 2017 to September 2019,78 patients with early ACI were selected,they were divided into the two groups with 39 cases in each group.The observation group was treated with rt-PA intravenous thrombolysis.The control group was treated with ozagrel sodium.The therapeutic effects of the two groups were compared.Results:The NIHSS score and adverse reaction rate of the observation group was significantly lower than that of the control group,the total effective rate and the Barthel index was significantly higher than that of the control group,the differences were statistically significant(P<0.05).Conclusion:rt-PA intravenous thrombolysis can improve the prognosis and the therapeutic effect of patients with early ACI,and it is safe.
作者
李志勇
吴树德
张淋莉
Li Zhiyong;Wu Shude;Zhang Linli(Department of Neurology,the People's Hospital of Jingzhou Miao and Dong Autonomous County,Hunan Huaihua 418400)
出处
《中国社区医师》
2020年第16期52-53,共2页
Chinese Community Doctors
