摘要
血管周围间隙(Perivascular Spaces, PVS)在磁共振中可以观察到与脑脊液信号相同,T2WI序列为高信号,T2FLAIR序列中为低信号,多发位置为半卵圆中心、基底节区、海马及中脑,形状多为圆形、卵圆形或者线性。PVS直径大于2 mm,但一般不超过3 mm,由于年龄的增长或脑淋巴系统循环障碍致使PVS逐渐扩张,形成脑血管周围间隙扩大(Enlarged Perivascular Spaces, EPVS),尤其与脑小血管疾病显著相关,因此EPVS可以作为影像诊断中的一种标志物,与神经系统中多个疾病的发生发展紧密相连。本文将对临床中神经系统某些相关疾病相关机制与EPVS产生关系的研究现状进行综述,以加深在脑影像学中EPVS的认知,提高对EPVS的重视,从而达到早期预防和诊断临床疾病的目的。
Perivascular Spaces (PVS) can be observed in MRI that the signals are the same as those in cerebrospinal fluid, with high signals in T2WI sequences and low signals in T2FLAIR sequences. The multiple locations are the center of the hemioval, basal ganglia, hippocampus and midbrain, and the shapes are mostly round, oval or linear. The diameter of PVS is greater than 2 mm, but generally no more than 3 mm. Due to the growth of age or cerebral glymphatic system circulation disorders, PVS gradually expands, forming the Enlarged Perivascular Spaces (EPVS), which is especially significantly related to brain small vessel diseases. Therefore, EPVS can be used as a marker in imaging diagnosis and is closely related to the occurrence and development of multiple diseases in the nervous system. In this paper, we will review the current research status of the relationship between EPVS and the related mechanisms of some neurological diseases in clinical practice, so as to deepen the cognition of EPVS in brain imaging and improve the attention paid to EPVS, so as to achieve the purpose of early prevention and diagnosis of clinical diseases.
出处
《临床医学进展》
2024年第7期567-571,共5页
Advances in Clinical Medicine
