摘要
目的 观察耐甲氧西林金黄色葡萄球菌 (MRSA)在临床标本中的检出动态及对万古霉素的耐药性变化趋势。方法 检测 1966年～ 2 0 0 1年各年度各种临床标本中MRSAR的分离率 ,测量万古霉素对MRSA的抑菌环直径大小。结果 1996～ 2 0 0 0年 5年内MRSA检出率有逐年上升趋势 ,2 0 0 1年通过筛查MRSA携带者并采取消毒隔离措施后 ,2 0 0 1年MRSA检出率为 3 2 .1% ,与 2 0 0 0年 (4 5 .9% )、1999年检出率 (3 8.5 % )比较明显降低 ,与 1998年 (3 0 .2 % )接近。随着时间推移 ,各年度MRSA对万古霉素的抑菌圈直径逐年减小。结论 通过筛查MRSA携带者并采取严格的消毒隔离措施 ,可使MRSA的检出率下降。
Objective To survey the prevalence of meticillin resistant Staphylococcus aureus ( MRSA) and the change of drug resistance on vancomycin.Methods The incidence of MRSA isolated from all clinical samples during 1996 to 2001 was monitored and the diameters of the inhibition zone of clinical isolates(MRSA)for vancomycin were measured.Results The incidences of MRSA increased from 1996 to 2001.After monitoring MRSA infected patients and taking disinfection and isolation measures,the incidence of MRSA in 2001(32.1%)was declined apparently,comparing to that in 2000(45.9%)and 1999(38.5%),which is similar with the incidence in 1998(30.2%).As time passing on,the diameters of the inhibition zone of MRSA on vancomycin were reducing year by year.Conclusion By monitoring MRSA infected patients and taking measures of disinfection and isolation,the incidence of MRSA was declined.The sensitivity of MRSA on vancomycin was reducing year by year.
出处
《临床内科杂志》
CAS
北大核心
2003年第11期571-573,共3页
Journal of Clinical Internal Medicine
