摘要
目的 :探讨肿瘤坏死因子 α(TNF α)和白细胞介素 6(IL 6)在癫痫患儿血清中的变化及临床意义。方法 :采用双抗体夹心酶联免疫吸附法 (ELISA)对 3 4例癫痫患儿和 2 3例正常对照儿童血清TNT α、IL 6水平进行测定。结果 :癫痫患儿血清TNF α、IL 6水平显著高于对照组 (P <0 .0 1)。抗癫痫药物对血清TNF α、IL 6水平无明显影响。结论 :细胞因子TNF α和IL
Objective:To observe the change of serum level of tumor necrosis factor α (TNF α) and interleukin 6 (IL 6) in epileptic children.Methods:Serum contents of TNF α and IL 6 were determined by ELISA in 34 epileptic children and 23 healthy controls.Results:Compared with control group,serum concentrations of TNF α and IL 6 were significantly increased( P< 0.01),and were not affected by antiepileptics in epileptic children.Conclusion:TNF α and IL 6 could be involved in the pathogenesis of epilepsy. [
出处
《广东医学院学报》
2003年第3期232-234,共3页
Journal of Guangdong Medical College
关键词
癫痫
患儿
血清
TNF-Α
IL-6
epilepsy
tumor necrosis factor α
interleukin 6
children
