期刊文献+

复苏周期中不同发育时间与不同数量囊胚解冻移植的临床结局与影响因素

Clinical outcomes and influencing factors of different development time and different number of blastocysts thawed transplantation in the resuscitation cycle
下载PDF
导出
摘要 目的探讨复苏周期中不同发育时间与不同数量囊胚解冻移植的临床结局与影响因素。方法选取2020年1月至2021年12月在赣州市妇幼保健院生殖医学中心进行体外受精-胚胎移植治疗的1008例患者作为研究对象,患者均第一次行复苏周期移植D5和D6解冻囊胚共1008个周期,根据囊胚不同分为D5双囊组(405个周期)、D5单囊组(322个周期)、D6双囊组(200个周期)、D6单囊组(81个周期)。比较4组临床资料和移植临床结局,并根据是否妊娠分为妊娠患者(n=618)、未妊娠患者(n=390),采用单因素和多因素Logistic回归分析移植临床结局的影响因素。结果D5双囊组妊娠率高于D5单囊组、D6单囊组,多胎妊娠率高于D5单囊组、D6双囊组、D6单囊组,D5单囊组妊娠率低于D6双囊组,高于D6单囊组,多胎妊娠率低于D6双囊组,且D6双囊组妊娠率、多胎妊娠率均高于D6单囊组,差异有统计学意义(P<0.05)。妊娠患者男、女年龄20~30岁与D5囊胚占比高于未妊娠患者,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,移植囊胚天数D5是移植临床结局的保护因素(P<0.05)。结论复苏周期移植选择D5单囊胚移植有利于母婴安全保护,降低多胎妊娠发生,而D6囊胚可考虑移植2枚改善临床妊娠结局,若患者同时拥有D5和D6优质囊胚,移植D5囊胚可提高妊娠率。 Objective To explore the clinical outcomes and influencing factors of different development time and different number of blastocysts thawed transplantation in the resuscitation cycle.Methods 1008 patients who underwent in vitro fertilization-embryo transfer in the Reproductive Medicine Center of Ganzhou Maternal and Child Health Hospital from January 2020 to December 2021 were selected as the research subjects,all pa-tients underwent the first resuscitation cycle to transfer D5 and D6 thawed blastocysts for a total of 1008 cycles,and they were divided into the D5 double capsule group(405 cycles),the D5 single capsule group(322 cycles),the D6 double capsule group(200 cycles),the D6 single capsule group(81 cycles)according to the different blastocysts.The clinical data and clinical outcomes among the four groups were compared,and the patients were divided into the pregnant patients(n=618)and the non-pregnant patients(n=390)according to whether they were pregnant or not,univariate and multivariate Logistic regression analysis was used to analyze the influencing factors of clinical outcomes of transplantation.Results The preg-nancy rate of D5 double capsule group was higher than that in the D5 single capsule group and the D6 single capsule group,the multiple pregnancy rate was higher than that in the D5 single capsule group,the D6 double capsule group and the D6 single capsule group,the pregnancy rate in the D5 single capsule group was lower than that in the D6 double capsule group,higher than that in the D6 single capsule group,the multiple pregnancy rate was lower than that in the D6 double capsule group,and the pregnancy rate and multiple pregnancy rate in the D6 double capsule group were higher than those in the D6 single capsule group,the differences were statistically significant(P<0.05).The proportion of male and female patients aged 20-30 years and D5 blastocysts in pregnant patients was higher than that in non-pregnant patients,and the difference was statistically significant(P<0.05).Multivariate Logistic re
作者 周龙萍 谢丽松 赖丽丹 廖宝琼 刘小舟 ZHOU Longping;XIE Lisong;LAI Lidan;LIAO Baoqiong;LIU Xiaozhou(Ganzhou Maternal and Child Health Hospital,Ganzhou,Jiangxi,341000,China)
出处 《当代医学》 2024年第7期66-69,共4页 Contemporary Medicine
关键词 复苏周期 囊胚 解冻 移植 Resuscitation cycle Blastocyst Defrost Transplantation
  • 相关文献

参考文献15

二级参考文献74

共引文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部