期刊文献+

静脉用丙种球蛋白联合地塞米松治疗儿童免疫性血小板减少症的疗效探讨

下载PDF
导出
摘要 目的:分析儿童免疫性血小板减少症(ITP)静脉用丙种球蛋白(GG)联合地塞米松治疗的效果。方法:选取64例儿童ITP患儿进行研究分析,病例选取时间为2021年2月—2022年2月,采取随机抽签模式均分两组,将行地塞米松治疗的32例患者设为参考组,将行静注丙种球蛋白联合地塞米松治疗的32例患者设为试验组。以治疗有效率、血小板指标、血常规指标、免疫指标及不良反应来评价两组治疗效果。结果:试验组治疗有效率高于参考组(P<0.05)。试验组血小板指标优于参考组(P<0.05)。血常规指标中,治疗后试验组PLT更高(P<0.05),WBC更低(P<0.05)。试验组各免疫指标均高于参考组(P<0.05)。两组不良反应对比差异不明显(P>0.05)。结论:儿童ITP行静脉用GG联合地塞米松治疗效果确切,能够改善患儿血小板指标、血常规指标,提升其免疫力,同时该治疗方法安全性高,能够减少不良反应产生,进而提高治疗效果。
作者 田立
出处 《北方药学》 2024年第4期113-115,共3页 Journal of North Pharmacy
  • 相关文献

二级参考文献65

  • 1Ruggeri M,Fortuna S,Rodeghiero F.Heterogeneity of terminology and clinical definitions in adult idiopathic thrombocytopenic purpura:a critical appraisal from a systematic review of the literature[J].Haematologica,2008,93(1):98-103. 被引量:1
  • 2Rodeghiero F,Stasi R,Gernsheimer T,et al.Standardiza-tion of terminology,definitions and outcome criteria in immune thrombocytopenic purpura of adults and children:report from an international working group[J].Blood,2009,113(11):2386-2393. 被引量:1
  • 3Bromberg ME.Immune thrombocytopenic purpura-the changing therapeutic landscape[J].N Engl J Med,2006,355(16):1643-1645. 被引量:1
  • 4Rosthoj S,Hedlund-Treutiger I,Rajantie J,et al.Dura-tion and morbidity of newly diagnosed idiopathic throm-bocytopenic purpura in children:a prospective nordic study of an unselected cohort[J].J Pediatr,2003,143(3):302-307. 被引量:1
  • 5Kuhne T,Buchanan GR,Zimmerman S,et al.A pros-pective comparative study of 2 540 infants and children with newly diagnosed idiopathic thrombocytopenic purpura (ITP) from the intercontinental childhood ITP study group[J].J Pediatr,2003,143(5):605-608. 被引量:1
  • 6Zeller B,Rajantie J,Hedlund-Treutiger I,et al.Child-hood idiopathic thrombocytopenic purpura in the Nordic countries:epidemiology and predictors of chronic di-sease[J].Acta Paediatr,2005,94(2):178-184. 被引量:1
  • 7British Committee for Standards in Haematology General Haematology Task Force.Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults,children and in pregnancy[J].Br J Haema-tol,2003,120(4):574-596. 被引量:1
  • 8George JN,Woolf SH,Raskob GE,et al.Idiopathic thrombocytopenic purpura:a practice guideline deve-loped by explicit methods for the American Society of Hematology[J].Blood,1996,88(1):3-40. 被引量:1
  • 9Tarantino MD,Madden RM,Fennewald DL,et al.Treatment of childhood acute immune thrombocytopenic purpura with anti-D immune globulin or pooled immune globulin[J].J Pediatr,1999,134(1):21-26. 被引量:1
  • 10Gaines AR.Disseminated intravascular coagulation asso-ciated with acute hemoglobinemia or hemoglobinuria following Rh(O)(D) immune globulin intravenous administration for immune thrombocytopenic purpura[J].Blood,2005,106(5):1532-1537. 被引量:1

共引文献39

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部