摘要
随着全球肥胖和老年人口数量的不断增加,肌少性肥胖的患病率持续上升,正成为全球流行的公共卫生问题。肌少性肥胖不仅会增加癌症的发生率,且在不同癌症类型中还与较差的临床结局有关,如手术并发症、死亡风险增加,甚至也可能对化疗产生影响,因此,肌少性肥胖逐渐成为癌症患者预后的重要指标。然而关于肌少性肥胖与癌症的关系,国内相关研究有限。本文旨在对肌少性肥胖的定义和诊断、肌少性肥胖与癌症的临床相关性及机制进行综述,以期为我国今后的临床实践提供参考。
As the global prevalence of obesity and the elderly population continues to increase,the incidence of sarcopenic obesity is also on the rise and becoming a global public health concern.Sarcopenic obesity not only increases the incidence of cancer,but is also associated with poor clinical outcomes in various cancers,such as surgical complications,increased risk of death,and possibly even an impact on chemotherapy as well.Therefore,sarcopenic obesity is emerging as an important indicator of prognosis in cancer patients.However,there are limited relevant studies on the association between sarcopenic obesity and cancer in China.This article reviews the definition and diagnosis of sarcopenic obesity,the clinical correlation between sarcopenic obesity and cancer,and the potential mechanisms,with a view to providing a reference for future clinical practice in China.
作者
徐春柳
刘悦文
郭琪
于莹
XU Chunliu;LIU Yuewen;GUO Qi;YU Ying(Graduate School of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Collage of Rehabilitation Sciences,Shanghai University of Medicine&Health Sciences,Shanghai 201318,China)
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2024年第2期267-274,共8页
Acta Academiae Medicinae Sinicae
基金
国家自然科学基金(82172552)。
关键词
肌少性肥胖
肥胖
癌症
肿瘤
sarcopenic obesity
obesity
cancer
carcinoma
