摘要
目的 探讨成年男性健康体检人群血红蛋白(Hb)水平与中性粒细胞/淋巴细胞(NLR)、中性粒细胞/清蛋白(NAR)及血脂的关系。方法 选取2022年10-12月在广西医科大学第一附属医院健康体检的264例成年男性为研究对象,131例为Hb升高组(Hb>160 g/L),133例为Hb正常组(120 g/L≤Hb≤160 g/L)。对研究对象的中性粒细胞绝对值(ANC)、清蛋白(Alb)、NLR、NAR、甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)和高密度脂蛋白胆固醇(HDL-C)水平进行检测与分析。结果 Hb升高组的ANC、Alb、NLR、NAR、TG、TC、LDL-C水平高于Hb正常组,HDL-C水平低于Hb正常组,差异均有统计学意义(P<0.05)。Hb升高组的ANC、TG、TC、LDL-C、HDL-C的异常发生率及血脂异常发生率均高于Hb正常组,差异均有统计学意义(P<0.05)。二元Logistic回归分析结果显示,TC、LDL-C水平升高和HDL-C水平下降是成年男性体检者Hb水平升高的独立危险因素(P<0.05)。结论 当成年健康男性Hb>160 g/L时,需要检查评估血脂及心脑血管状况,及早采取预防干预措施,防止心脑血管疾病的发生。
Objective To investigate the relationship between hemoglobin(Hb)level with neutrophil/lymphocyte(NLR),neutrophil/albumin(NAR)and blood lipid in healthy adult males undergoing physical examination.Methods A total of 264 adult males undergoing physical examination in First Affiliated Hospital of Guangxi Medical University from October to December 2022 were selected as the study subjects,131 cases in the Hb elevation group(Hb>160 g/L)and 133 cases in the Hb normal group(120 g/L≤Hb≤160 g/L).The absolute neutrophil count(ANC),albumin(Alb),NLR,NAR,triglyceride(TG),total cholesterol(TC),low density lipoprotein cholesterol(LDL-C)and high density lipoprotein cholesterol(HDL-C)of the subjects were detected and analyzed.Results The levels of ANC,Alb,NLR,NAR,TG,TC and LDL-C in the Hb elevation group were higher than those in the Hb normal group,the HDL-C level was lower than that in the Hb normal group,and the differences were statistically significant(P<0.05).The occurrence rates of ANC,TG,TC,LDL-C,HDL-C abnormality and blood lipid abnormality in the Hb elevation group all were higher than those in the Hb normal group,and the differences were statistically significant(P<0.05).The binary Logistic regression analysis results showed that TC level increase,LDL-C level increase and HDL-C level decrease were the independent risk factors for Hb elevation in adult males undergoing physical examination(P<0.05).Conclusion When Hb>160 g/L in healthy adult males,the blood lipid and cardiovascular and cerebrovascular status should be detected and evaluated,and the preventive intervention measures should be taken as soon as possible to prevent the occurrence of cardiovascular and cerebrovascular diseases.
作者
陈欣雁
翟宁能
覃媛媛
林发全
CHEN Xinyan;ZHAI Ningneng;QIN Yuanyuan;LIN Faquan(Key Laboratory of Clinical Laboratory Medicine of Guangxi University/Department of Clinical Laboratory,First Affiliated Hospital of Guangxi Medical University,Nanning,Guangxi 530021,China)
出处
《检验医学与临床》
CAS
2023年第7期902-905,共4页
Laboratory Medicine and Clinic
