摘要
目的探讨无创正压通气治疗呼吸系统疾病新生儿的临床疗效。方法回顾性分析呼吸系统疾病新生儿84例。根据治疗方式不同分为经鼻持续性气道正压通气(NCPAP)组(观察组)和正常对照组,各42例。比较两组治疗前及通气24h后血氧饱和度(SpO_(2))、血氧分压(PaO_(2)),二氧化碳分压(PaCO_(2))变化,比较两组通气时间、住院时间、呼吸暂停及有创通气发生率。结果治疗前,两组SpO_(2)、PaO_(2)、PaCO_(2)比较差异无统计学意义(P>0.05);通气24h后,两组SpO_(2)、PaO_(2)均升高,PaCO_(2)均降低(P<0.05),但观察组SpO_(2)、PaO_(2)均高于对照组,PaCO_(2)低于对照组(P<0.05)。观察组住院时间比对照组短,呼吸暂停率低于对照组(P<0.05)。结论NCPAP对呼吸系统疾病新生儿的疗效满意,患儿住院时间更短,呼吸暂停率更低。
Objective To investigate the clinical effect of noninvasive positive pressure ventilation in the treatment of neonatal respiratory diseases.Methods A retrospective analysis of 84 cases of neonatal respiratory diseases treated.According to different treatment methods,they were divided into nasal continuous positive airway pressure(nCPAP)group(observation group)and normal control group,42 cases in each group.Blood oxygen saturation(SpO_(2)),partial pressure of oxygen(PaO_(2))and partial pressure of carbon dioxide(PaCO_(2))before treatment and 24 hours after ventilation were compared between the two groups.Results Before treatment,there was no significant difference in SpO_(2),PaO_(2) and PaCO_(2) between the two groups(P>0.05);After 24 hours of ventilation,SpO_(2) and PaO_(2) increased and PaCO_(2) decreased in both groups(P<0.05),but SpO_(2) and PaO_(2) in the observation group were higher than those in the control group,and PaCO_(2) in the observation group was lower than that in the control group(P<0.05).The hospitalization time of the observation group was shorter than that of the control group,and the apnea rate was lower than that of the control group(P<0.05).Conclusion NCPAP is effective for newborns with respiratory diseases,with shorter hospital stay and lower apnea rate.
作者
谭改玲
黄颖璇
李妹清
刘玲
Tan gailing;Huang yingxuan;Li Meiqing;Liu Ling(Department of Pediatrics,The Third Affiliated Hospital of Guangdong Medical University,Longjiang Hospital,Shunde District,Foshan528318,China)
出处
《哈尔滨医药》
2022年第4期28-29,共2页
Harbin Medical Journal
关键词
无创正压通气
新生儿
呼吸系统疾病
疗效
Noninvasive positive pressure ventilation
Newborn
Respiratory diseases
Curative effect
