摘要
目的探讨经鼻间歇正压通气(NIPPV)治疗新生儿呼吸窘迫综合征的临床疗效。方法选择2019年2月24日至2020年12月24日在我院新生儿科接受治疗的64例新生儿呼吸窘迫综合征患儿作为对象,按随机数字法将其分为观察组和对照组,各32例。对照组给予经鼻持续气道正压通气(NCPAP)治疗,观察组给予经鼻间歇正压通气(NIPPV)治疗,连续治疗12h后观察两组患者临床疗效,比较两组治疗后临床症状,治疗前后血气变化水平,辅助通气时间、住院时间和氧疗时间。结果观察组治疗总有效率90.63%(29/32),明显高于对照组62.50%(20/32)(χ2=4.746,P=0.026);观察组治疗后12h PaO2、pH和SaO2水平高于对照组(P<0.05);PaCO2水平低于对照组(P<0.05);观察组辅助通气时间、住院时间和氧疗时间均短于对照组(P<0.05)。结论NIPPV治疗新生儿呼吸窘迫综合征能有效改善患儿的临床症状,改善患儿血气PaO2、pH和SaO2水平,降低PaCO2水平,缩短辅助通气时间、住院时间和氧疗时间,促进患儿的康复,值得推广。
Objective To explore the clinical efficacy of nasal intermittent positive pressure ventilation(NIPPV)in the treatment of neonatal respiratory distress syndrome.Methods 64 children with neonatal respiratory distress syndrome who were treated in the neonatal department of our hospital from February 24,2019 to December 24,2020 were selected as subjects,and they were divided into observation group and control group according to the random number method,32 cases each.The control group was given nasal continuous positive airway pressure(NCPAP)treatment,and the observation group was given nasal intermittent positive pressure ventilation(NIPPV)treatment.After 12 hours of continuous treatment,the clinical efficacy of the two groups of patients was observed.The clinical symptoms,the blood gas changes,auxiliary ventilation time,hospital stay and oxygen therapy time were compared between the two groups.Results The total effective rate of treatment in the observation group was 90.63%(29/32),significantly higher than 62.50%(20/32)in the control group(χ2=4.746,P=0.026).The PaO2,pH and SaO2 levels of the than that of the control group(P<0.05).The auxiliary ventilation time,hospital stay and oxygen therapy time in the observation group were shorter than those in the control group(P<0.05).Conclusion NIPPV treatment of neonatal respiratory distress syndrome can effectively improve the clinical symptoms of children,improve their blood gas PaO2,pH and SaO2 levels,reduce PaCO2 levels,shorten the time of assisted ventilation,hospitalization and oxygen therapy,and promote children’s recovery,which is worth promoting.
作者
陈清
彭顺眉
杨苏强
CHEN Qing;PENG Shun-mei;YANG Su-qiang(Department of Pediatrics,People’s Hospital of Yuancheng District,Heyuan,Guangdong 517000)
出处
《智慧健康》
2021年第7期65-67,共3页
Smart Healthcare
基金
2019年河源市科技计划项目合同,项目编号:河科2019066
关键词
经鼻间歇正压通气
经鼻持续气道正压通气
新生儿呼吸窘迫综合征
临床症状
血气水平
Intermittent positive pressure ventilation through the nose
Continuous positive airway pressure through the nose
Neonatal respiratory distress syndrome
Clinical symptoms
Blood gas levels
