摘要
目的 通过在重症急性胰腺炎临床治疗上使用生长抑素联合泮托拉唑钠进行治疗,观察分析生长抑素联合泮托拉唑钠治疗此疾病的临床治疗效果。方法 采取暗数法选取新疆医科大学第五附属医院2021年1月-2021年6月治疗的15例重症急性胰腺炎患者,将其划分为两组即对照组(n=7,采取单纯生长抑素治疗)与观察组(n=8,在前者治疗基础上联合使用泮托拉唑钠治疗)。通过对两组患者实施不同的药物治疗措施对比其临床治疗效果。结果 ①观察组患者治疗总有效率为87.50%高于对照组患者的71.43%,存在统计学差异(P<0.05);②治疗前两组患者炎性因子在各方面无统计学差异(P>0.05),经过治疗后均呈上升趋势,但是观察组患者炎性因子在各方面的变化情况均优于对照组患者,组间存在统计学差异(P<0.05);③观察组患者临床相关观察指标恢复所需时间均短于对照组患者,组间所产生的差异具有统计学意义(P<0.05)。结论 在临床治疗重症急性胰腺炎疾病中使用泮托拉唑钠与生长抑素联合治疗其治疗效果良好且可以明显缓和患者各项炎症相关指标情况以及临床症状表现,安全性较高,有临床推广使用的价值与意义。
Objective To observe and analyze the clinical therapeutic effect of somatostatin combined with pantoprazole sodium in the treatment of severe acute pancreatitis.Methods The dark number method was used to select 15 patients with severe acute pancreatitis who were treated in our hospital from January 2021 to June 2021,and divided them into two groups,namely the control group (n=7,treated with somatostatin alone) and In the observation group (n=8,combined with pantoprazole sodium treatment based on the former treatment).The clinical treatment effects of the two groups of patients were compared by implementing different drug treatment measures.Results ①The total effective rate of treatment in the observation group was 87.50% higher than 71.43% in the control group,which was statistically different (P<0.05).②There was no significant difference in inflammatory factors between the two groups before treatment (P>0.05),but after treatment,they all showed an upward trend,the changes of inflammatory factors in the observation group were better than those in the control group (P<0.05).③The time required for the recovery of clinically relevant observation indicators in the observation group was shorter than that in the control group,and the difference between the groups was statistically significant (P<0.05).Conclusion The combination of pantoprazole sodium and somatostatin in the clinical treatment of severe acute pancreatitis has a good therapeutic effect and can significantly alleviate various inflammation-related indicators and clinical symptoms in patients.It is safe and has clinical symptoms.The value and significance of promotion.
作者
薄涛
杨健
胡雁飞
骆晓梅
BO Tao;YANG Jian;HU Yanfei;LUO Xiaomei(The Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang,830001)
出处
《智慧健康》
2022年第14期120-122,共3页
Smart Healthcare
关键词
生长抑素
泮托拉唑钠
重症急性胰腺炎
临床疗效
Somatostatin
Pantoprazole sodium
Severe acute pancreatitis
Clinical efficacy
