摘要
目的观察泮托拉唑钠联合生长抑素治疗重症急性胰腺炎的临床疗效。方法选取2016年1月至2018年12月126例重症急性胰腺炎患者为研究对象,根据患者入院时间先后顺序分为对照组与研究组,每组63例。对照组患者应用泮托拉唑钠治疗,研究组患者在对照组治疗基础上加用生长抑素治疗。比较两组患者的治疗效果、炎症因子水平、症状缓解时间及不良反应发生情况。结果研究组治疗总有效率高于对照组,炎症因子水平、症状缓解时间及不良反应发生率均显著低于对照组,差异有统计学意义(P<0.05)。结论联合应用泮托拉唑钠与生长抑素治疗重症急性胰腺炎患者,可减轻患者炎症反应,缩短症状缓解时间,降低不良反应发生率,提高临床疗效,安全有效,有临床推广应用价值。
Objective To observe the clinical efficacy of pantoprazole sodium combined with somatostatin on severe acute pancreatitis. Methods A total of 126 patients with severe acute pancreatitis from January 2016 to December 2018 were selected as the objects of study.The patients were divided into control group and research group according to the order of admission time, with 63 cases in each group. The patients in the control group were treated with semi-torazole sodium.The study group was treated with somatostatin on the basis of the control group. The treatment effect, inflammation factor level, symptom relief time and adverse reactions were compared between the two groups. Results The total effective rate in the study group was higher than that in the control group, and the levels of inflammatory factors, relief time of symptoms and incidence of adverse reactions in the study group were lower than those in the control group, the differences were significant(P<0.05). Conclusions The combination of pantoprazole sodium and somatostatin in the treatment of severe acute pancreatitis can reduce the inflammatory response, shorten the symptom relief time, reduce the adverse reactions, improve the clinical efficacy, which is safe and effective, and have clinical application value.
作者
王鑫
杨路
Wang Xin;Yang Lu(Department of Gastroenterology,Xinyang First People's Hospital,Xinyang 464000,China)
出处
《临床医学》
CAS
2019年第10期92-94,共3页
Clinical Medicine
关键词
泮托拉唑
生长抑素
重症急性胰腺炎
应用价值
Pantorpazole
Somatostatin
Severe acute pancreatitis
Application value
