摘要
试验旨在研究埋植和饲喂褪黑素对绵羊断奶后生长性能、氧化应激和免疫功能的影响。选用65~75日龄、体重19 kg左右的绵羊30只,随机分为5组,每组6个重复,对照组正常饲喂,埋植组分别颈部皮下埋植60mg和90mg褪黑素1次,饲喂组按绵羊体重饲喂1、3mg/(kg·d)褪黑素,预试验30d,正试期60d。结果表明:与对照组相比,埋植60 mg和90 mg褪黑素可提高平均日增重(P<0.05),饲喂1 mg/kg褪黑素也可提高平均日增重(P<0.01);埋植90 mg褪黑素组的生长速率、饲喂1 mg/kg褪黑素组生长速率、体高、胸围、胸宽、胸深平均日增长均提高(P<0.01);埋植90 mg褪黑素组体高平均日增长(P<0.01)、胸深平均日增长(P<0.05)也均得到提高;饲喂3 mg/kg褪黑素组体高、胸围平均日增长提高(P<0.05);埋植90mg褪黑素组和饲喂1mg/kg褪黑素组皮质醇(COR)浓度降低(P<0.01),饲喂1mg/kg褪黑素组超氧化物歧化酶(SOD)含量升高(P<0.05)、丙二醛(MDA)降低(P<0.01);饲喂1 mg/kg褪黑素免疫球蛋白A(IgA)、免疫球蛋白M(IgM)含量升高(P<0.05)。本试验条件下,褪黑素能够缓解绵羊断奶氧化应激,提高血清抗氧化能力,增强机体免疫能力,提高绵羊的生长性能。
The aim of this experiment was to study the effects of implanting and feeding melatonin on growth performance,oxidative stress and immune function of sheep after weaning.Thirty sheep aged 65-75 days were randomly divided into 5 groups with 6 replicates in each group.Melatonin was subcutaneously implanted 60 mg or 90 mg once in the neck,respectively.Sheep were fed with 1 or 3 mg/(kg·d)melatonin according to their body weight.The pre-experiment lasted for 30 days and the experiment lasted for 60 days.The results showed as follows:the average daily gain of 60 mg and 90 mg melatonin implantation was significantly increased(P<0.05),and the average daily gain of 1 mg/kg melatonin feeding was significantly increased(P<0.01);The growth rate of implanting 90 mg and feeding 1 mg/kg melatonin was significantly increased(P<0.01);The average daily increase of melatonin height,chest circumference,chest width and chest depth in 1 mg/kg diet were significantly increased(P<0.01);The average daily growth of body height and chest depth were significantly increased by 90 mg melatonin implantation(P<0.01),and the average daily growth of body height and chest circumference were significantly increased by 3 mg/kg MT(P<0.05).Implanting 90 mg of melatonin and feeding 1 mg/kg of melatonin significantly decreased the concentration of cortisol(P<0.01),feeding 1 mg/kg of melatonin SOD content was significantly increased(P<0.05),malondialdehyde was significantly decreased(P<0.01).The contents of immunoglobulin A and immunoglobulin M in 1 mg/kg melatonin diet were significantly increased(P<0.05).Under the conditions of this study,melatonin can relieve oxidative stress of weaning sheep,improve serum antioxidant capacity,enhance the immune capacity of the body,and improve the growth performance of sheep.
作者
王梓颐
徐尚
任艳玲
周强
吴昊
马文奎
阎来庆
张鲁
刘奋泽
沈志强
杨开伦
连正兴
阿布力孜•吾斯曼
刘国世
WANG Ziyi;XU Shang;REN Yanling;ZHOU Qiang;WU Hao;MA Wenkui;YAN Laiqing;ZHANG Lu;LIU Fenze;SHEN Zhiqiang;YANG Kailun;LIAN Zhengxing;WUSIMAN Abulizi;LIU Guoshi(College of Animal Science,Xinjiang Agricultural University,Xinjiang Urumqi 830052,China;College of Animal Science and Technology,China Agricultural University,Beijing 100193,China;Inner Mongolia Golden Grassland Ecological Technology Group Co.Ltd.,Inner Mongolia Bayannaoer 015115,China;Shandong Province Lowland Sheep Breeding Technology Research and Promotion Center,Shandong Binzhou 256600,China)
出处
《中国畜牧杂志》
CAS
北大核心
2022年第4期195-200,共6页
Chinese Journal of Animal Science
基金
国家转基因育种重大专项(2016ZX08008003、2018ZX0800801B)
内蒙古金草原生态科技集团有限公司与中国农业大学横向合作项目
国家自然科学基金重点项目(31830091)。
关键词
褪黑素
绵羊
生长性能
氧化应激
免疫指标
Melatonin
Sheep
Growth performance
Oxidative stress
Immune indicators
