摘要
目的:研究上消化道大出血(UGB)患者行生长抑素联合急诊内镜治疗效果。方法:选取2019年1月-2020年1月中山市人民医院收治的50例UGB患者,按照随机数字表法分为常规组和联合组,每组25例。常规组采用常规疗法治疗,联合组采用生长抑素联合急诊内镜治疗。比较两组凝血功能、血液流变学、临床指标,以及止血成功率、再出血率。结果:治疗前,两组部分凝血酶原时间(APTT)、凝血酶原时间(PT)、血小板计数(PLT)水平比较,差异均无统计学意义(P>0.05);治疗后,两组APTT、PT均短于治疗前,PLT均高于治疗前,且联合组APTT、PT均短于常规组,PLT高于常规组,差异均有统计学意义(P<0.05)。治疗前,两组红细胞计数、血细胞比容、纤维蛋白原(FIB)比较,差异均无统计学意义(P>0.05);治疗后,两组红细胞计数、血细胞比容及FIB均高于治疗前,且联合组均高于常规组,差异均有统计学意义(P<0.05)。联合组呕血消失、大便潜血转阴及住院时间均优于常规组,差异均有统计学意义(P<0.05)。联合组止血成功率为92.00%,高于常规组的68.00%;联合组再出血率为4.35%,低于常规组的35.29%,差异均有统计学意义(P<0.05)。结论:生长抑素+急诊内镜治疗上消化道大出血能提高效果,值得推荐。
Objective:To study the effect of Somatostatin combined with emergency endoscopy in the treatment of upper gastrointestinal hemorrhage(UGB).Method:A total of 50 patients with UGB admitted to Zhongshan People’s Hospital from January 2019 to January 2020 were selected,and they were divided into conventional group and combined group according to random number table method,with 25 patients in each group.The conventional group was treated with conventional therapy,and the combined group was treated with Somatostatin combined with emergency endoscopy.Coagulation function,hemorheology,clinical indicators,success rate of hemostasis and rebleeding rate were compared between two groups.Result:Before treatment,there were no significant differences in partial prothrombin time(APTT),prothrombin time(PT)and platelet count(PLT)between two groups(P>0.05);after treatment,APTT and PT in both groups were shorter than those before treatment,and PLT in both groups were higher than those before treatment,and APTT and PT in the combined group were shorter than those in the conventional group,and PLT in the combined group was higher than that in the conventional group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in erythrocyte count,hematocrit and fibrinogen(FIB)between two groups(P>0.05);after treatment,erythrocyte count,hematocrit and FIB in both groups were higher than those before treatment,and those in the combined group were higher than those in the conventional group,the differences were statistically significant(P<0.05).The hematemesis disappeared,fecal occult blood turned negative and hospital stay in the combined group were better than those in the conventional group,the differences were statistically significant(P<0.05).The success rate of hemostasis in the combined group was 92.00%,which was higher than 68.00%in conventional group,the rebleeding rate in the combined group was 4.35%,which was lower than 35.29%in the conventional group,the differences were stati
作者
杨玉宇
刘智尚
丁信
叶淑尧
YANG Yuyu;LIU Zhishang;DING Xin;YE Shuyao(不详;Zhongshan People’s Hospital,Zhongshan 528400,China)
出处
《中外医学研究》
2022年第8期35-38,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
生长抑素
急诊内镜
上消化道大出血
Somatostatin
Emergency endoscopy
Upper gastrointestinal bleeding
